{"id":5691,"date":"2023-09-04T03:18:36","date_gmt":"2023-09-04T03:18:36","guid":{"rendered":"https:\/\/cm.vastapps.dev\/tcia-collection\/prostatex\/"},"modified":"2023-09-13T12:03:20","modified_gmt":"2023-09-13T12:03:20","slug":"prostatex","status":"publish","type":"tcia_collection","link":"https:\/\/cm.vastapps.dev\/tcia-collection\/prostatex\/","title":{"rendered":"PROSTATEX"},"featured_media":8230,"template":"","citation-tax":[],"cancer_types":["Prostate Cancer"],"citations":[4640,4641,2925],"collection_doi":"10.7937\/K9TCIA.2017.MURS5CL","collection_download_info":"<u> <strong>Note:<\/strong> <\/u>  The following download links will download the entire collection. See the Detailed Description section of this page for information about subsets specific to the PROSTATEx challenges.\n\nClick the Versions tab for more info about data releases.","collection_downloads":[5270,5272,5273],"full_export":"<div class=\"contentLayout2\">\n<div class=\"columnLayout two-right-sidebar\" data-layout=\"two-right-sidebar\">\n<div class=\"cell normal\" data-type=\"normal\">\n<div class=\"innerCell\">\n<h1 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Summary\">Summary<\/h1><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">PROSTATEx has been superseded by PI-CAI<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p>The ProstateX dataset (both training and testing cases) have been included in the PI-CAI Public Training and Development dataset. As such, ProstateX as a benchmark has been deprecated and is superseded by the PI-CAI challenge. PI-CAI is an all-new grand challenge, with over 10,000 carefully-curated prostate MRI exams to validate modern AI algorithms and estimate radiologists' performance at clinically significant prostate cancer detection and diagnosis. Key aspects of the study design have been established in conjunction with an international, multi-disciplinary scientific advisory board (16 experts in prostate AI, radiology and urology)\u00a0 - to unify and standardize present-day guidelines, and to ensure meaningful validation of prostate-AI towards clinical translation. Please refer to <a href=\"https:\/\/pi-cai.grand-challenge.org\" class=\"external-link\" rel=\"nofollow\">https:\/\/pi-cai.grand-challenge.org<\/a> for more information.<\/p><\/div><\/div><p><br\/>This collection is a retrospective set of prostate MR studies. All studies included T2-weighted (T2W), proton density-weighted (PD-W), dynamic contrast enhanced (DCE), and diffusion-weighted (DW) imaging. The images were acquired on two different types of Siemens 3T MR scanners, the MAGNETOM Trio and Skyra. T2-weighted images were acquired using a turbo spin echo sequence and had a resolution of around 0.5 mm in plane and a slice thickness of 3.6 mm. The DCE time series was acquired using a 3-D turbo flash gradient echo sequence with a resolution of around 1.5 mm in-plane, a slice thickness of 4 mm and a temporal resolution of 3.5 s. The proton density weighted image was acquired prior to the DCE time series using the same sequence with different echo and repetition times and a different flip angle. Finally, the DWI series were acquired with a single-shot echo planar imaging sequence with a resolution of 2 mm in-plane and 3.6 mm slice thickness and with diffusion-encoding gradients in three directions. Three b-values were acquired (50, 400, and 800), and subsequently, the ADC map was calculated by the scanner software. All images were acquired without an endorectal coil.<\/p><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-AccessingthePROSTATExChallengeDataSets\"><span>Accessing the PROSTATEx Challenge Data Sets<\/span><\/h3><p><span style=\"color: rgb(33,33,33);\">The PROSTATEx Challenge (&quot;<\/span> <span style=\"color: rgb(33,33,33);\">SPIE-AAPM-NCI Prostate MR Classification Challenge\u201d) focused on\u00a0<\/span> <span style=\"color: rgb(33,33,33);\">quantitative image analysis methods for the diagnostic classification of clinically significant prostate cancers and was held in conjunction with the 2017 SPIE Medical Imaging Symposium<\/span><span style=\"color: rgb(33,33,33);\">. \u00a0PROSTATEx ran from November 21, 2016 to January 15, 2017, though a<span>\u00a0&quot;live&quot; version has also been established at\u00a0<a href=\"https:\/\/prostatex.grand-challenge.org\" class=\"external-link\" rel=\"nofollow\">https:\/\/prostatex.grand-challenge.org<\/a> <\/span> <span>\u00a0which serves as an ongoing way for researchers to benchmark their performance for this task.<\/span> <\/span><\/p><p><span style=\"color: rgb(33,33,33);\">The PROSTATEx-2 Challenge (&quot;<\/span> <span style=\"color: rgb(33,33,33);\">SPIE-AAPM-NCI\u00a0<\/span> <span style=\"color: rgb(33,33,33);\">Prostate MR Gleason Grade Group Challenge&quot;<\/span> <span style=\"color: rgb(33,33,33);\">) ran from <span style=\"color: rgb(33,33,33);\">May 15, 2017 to June 23, 2017 and\u00a0<\/span>was focused on\u00a0<\/span> <span style=\"color: rgb(33,33,33);\">the development of quantitative multi-parametric MRI biomarkers for the determination of Gleason Grade Group in prostate cancer.\u00a0 It was\u00a0<\/span> <span style=\"color: rgb(33,33,33);\">held in conjunction with the 2017 AAPM Annual Meeting (see\u00a0<\/span> <a href=\"http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\" class=\"external-link\" rel=\"nofollow\">http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2<\/a> <span style=\"color: rgb(33,33,33);\">)<\/span> <span style=\"color: rgb(33,33,33);\">.\u00a0<\/span><\/p><p><span style=\"color: rgb(33,33,33);\"> <span style=\"color: rgb(33,33,33);\">Supplemental data and instructions specific to both challenges can be found on the Detailed Description tab below.\u00a0\u00a0<\/span> <br\/><\/span><\/p><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Acknowledgements\">Acknowledgements<\/h3><p>The prostate MR imaging was performed at the Radboud University Medical Centre (Radboudumc) in the Prostate MR Reference Center under supervision of prof. Dr. Barentsz. The Radboudumc is located in Nijmegen, The Netherlands. The dataset was collected and curated for research in computer aided diagnosis of prostate MR under supervision of Dr. Huisman, Radboudumc.<\/p><\/div>\n<\/div>\n<div class=\"cell aside\" data-type=\"aside\">\n<div class=\"innerCell\">\n<p><span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\"><img class=\"confluence-embedded-image\" draggable=\"false\" width=\"325\" src=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/embedded-page\/Public\/SPIE-AAPM-NCI%20PROSTATEx%20Challenges%20(PROSTATEx)\/image2016-10-6%2014:6:27.png?api=v2\"><\/span><\/p><p><span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\"><img class=\"confluence-embedded-image\" draggable=\"false\" width=\"325\" src=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/embedded-page\/Public\/SPIE-AAPM-NCI%20PROSTATEx%20Challenges%20(PROSTATEx)\/PROSTATEx-2_logo.jpg?api=v2\"><\/span><\/p><\/div>\n<\/div>\n<\/div>\n<div class=\"columnLayout two-right-sidebar\" data-layout=\"two-right-sidebar\">\n<div class=\"cell normal\" data-type=\"normal\">\n<div class=\"innerCell\">\n<div class=\"tab-style-builtin\"><div class=\"localtabs-macro\"><div class=\"aui-tabs horizontal-tabs\" role=\"application\" data-aui-responsive=\"true\"><ul class=\"tabs-menu\"><li class=\"menu-item bv-localtab  active-tab \"><a href=\"#236916562fb510193acf4c9fab263fa09f217d7b\"><strong>Data Access<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#23691656860763166b154d3b8294e6ff0c206fa5\"><strong>Detailed Description<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#23691656a5ea77cf7e964d29ac5f942cc3fc9bb1\"><strong>Citations &amp; Data Usage Policy<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#23691656a47beae550a34ad991e9eec3f80a393d\"><strong>Versions<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#23691656b6a68cb843e0491a8e56d80d1e46f164\"><strong>Publications that Leveraged this Dataset<\/strong><\/a> <\/li><\/ul><div class=\"tabs-pane  active-pane \" id=\"236916562fb510193acf4c9fab263fa09f217d7b\" active=\"true\" name=\"Data Access\" ><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-DataAccess\">Data Access<\/h3><p><span style=\"color: rgb(255,0,0);\"> <u> <strong>Note:<\/strong> <\/u> <\/span> The following download links will download the entire collection. See the Detailed Description section of this page for information about subsets specific to the PROSTATEx challenges.<\/p><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 64.0858%;\"><colgroup><col style=\"width: 33.0915%;\"\/><col style=\"width: 41.3538%;\"\/><col style=\"width: 25.5486%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Download images (15.1 GB DICOM)<\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx-v1-doiJNLP.tcia?version=1&amp;modificationDate=1534787029451&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=PROSTATEx\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><\/p><\/div><p class=\"auto-cursor-target\"><span style=\"color: rgb(33,37,41);\">(Download requires<span>\u00a0<\/span><\/span><a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\" style=\"text-decoration: none;text-align: left;\">NBIA Data Retriever<\/a><span style=\"color: rgb(33,37,41);\">)<\/span><\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\">Ktrans images (.mhd) and Lesion Info (.csv)<\/td><td class=\"confluenceTd\">See Detailed Description tab<\/td><td class=\"confluenceTd\"><br\/><\/td><\/tr><tr><td class=\"confluenceTd\">Test set reference standard (csv)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/pages\/viewpage.action?pageId=23691656&amp;preview=%2F23691656%2F127665000%2FProstateX-Findings-Test.csv\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p class=\"auto-cursor-target\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>Click the Versions tab for more info about data releases.<\/p><p>\n<h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-AdditionalResourcesforthisDataset\">Additional Resources for this Dataset<\/h3>\n<p>The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.<\/p><\/p><ul><li class=\"auto-cursor-target\"><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=prostatex\" class=\"external-link\" rel=\"nofollow\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li><\/ul><h3 style=\"text-align: left;\" id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-ThirdPartyAnalysesofthisDataset\">Third Party Analyses of this Dataset<\/h3><p>TCIA encourages the community to\u00a0<a href=\"http:\/\/www.cancerimagingarchive.net\/analysis-results\/\" class=\"external-link\" rel=\"nofollow\">publish your analyses of our datasets<\/a>. Below is a list of such third party analyses published using this Collection:<\/p><ul><li><a href=\"https:\/\/doi.org\/10.7937\/TCIA.2019.DEG7ZG1U\" class=\"external-link\" rel=\"nofollow\">High Resolution Prostate Segmentations for the ProstateX-Challenge<\/a>\u00a0<\/li><li><a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/oaAvB\" rel=\"nofollow\">PROSTATEx Zone Segmentations<\/a><\/li><\/ul><\/div><div class=\"tabs-pane \" id=\"23691656860763166b154d3b8294e6ff0c206fa5\" name=\"Detailed Description\" ><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-DetailedDescription\">Detailed Description<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <\/colgroup><tbody><tr><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p>Collection Statistics<\/p><\/div><\/th><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p>Radiology Imaging<\/p><\/div><\/th><\/tr><tr><td class=\"confluenceTd\"><p>Modalities<\/p><\/td><td class=\"confluenceTd\"><p>MR<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Participants<\/p><\/td><td class=\"confluenceTd\"><p>346<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Studies<\/p><\/td><td class=\"confluenceTd\"><p>349<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Series<\/p><\/td><td class=\"confluenceTd\"><p>18,321<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Images<\/p><\/td><td class=\"confluenceTd\"><p>309,251<\/p><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\">Images Size (GB)<\/td><td colspan=\"1\" class=\"confluenceTd\">15.1<\/td><\/tr><\/tbody><\/table><\/div><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-PROSTATExChallenge(November21,2016toFebruary16,2017)\">PROSTATEx Challenge (November 21, 2016 to February 16, 2017)<\/h3><p>SPIE, along with the support of the American Association of Physicists in Medicine (AAPM) and the National Cancer Institute (NCI), conducted a \u201cGrand Challenge\u201d on quantitative image analysis methods for the diagnostic classification of clinically significant prostate lesions. \u00a0For more details, go to\u00a0<a href=\"https:\/\/prostatex.grand-challenge.org\/\" class=\"external-link\" rel=\"nofollow\">https:\/\/prostatex.grand-challenge.org\/<\/a>\u00a0.\u00a0\u00a0<\/p><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Training and test cohorts along with supplemental Ktrans images and lesion information can be obtained separately using the following options for download:<\/span> <\/span><\/p><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\" class=\"confluenceTh\">Data Type<\/th><th colspan=\"1\" class=\"confluenceTh\"><p>Training Cohort<\/p><p>(204 subjects)<\/p><\/th><th colspan=\"1\" class=\"confluenceTh\"><p>Test Cohort<\/p><p>(140 subjects)<\/p><\/th><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download images (DICOM)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx-train.tcia?version=1&amp;modificationDate=1534787030035&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\"><br\/><\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx-test.tcia?version=1&amp;modificationDate=1534787450806&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download Ktrans images (.mhd)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/app.box.com\/s\/y871i386j4o9rqwcsms5mqni63nojzx1\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/app.box.com\/s\/k3iofc0r3ktjnb4f7105lssdzjon95ie\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download lesion information (.zip)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateX-TrainingLesionInformationv2.zip?version=2&amp;modificationDate=1483479231532&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateX-TestLesionInformation.zip?version=2&amp;modificationDate=1483479234096&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download lesion reference thumbnails (.bmp)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateX-Screenshots-Train.zip?version=1&amp;modificationDate=1479401241653&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/app.box.com\/s\/7jn4jtd3pbi9rlurc4pvnkx554lnfljw\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">The images come in two encodings. The acquired MR is provided in DICOM encoding. Additionally Ktrans images are provided. They come in mhd format. Ktrans is a key pharmacokinetic parameter computed from the available Dynamic contrast enhanced T1-weighted series. Each patient has one study with several DICOM images and one Ktrans image. The Ktrans image is encoded in two files ProstateX-[ProxID]-Ktrans.[mhd\/zraw], where ProxID is the ProstateX patient identifier. The DICOM images comprise several Series each comprising several Instances. The DICOM files are documented in the ProstateX-Images.csv file. The columns in that file encode the following:<\/span> <\/span><\/p><ul><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ProxID \u2013 ProstateX patient identifier.<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Name \u2013 Series Description<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Studydate \u2013 Study Date<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">fid \u2013 Finding ID<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Pos \u2013 Scanner Coordinate position of the finding<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">WorldMatrix \u2013 Matrix describing image orientation and scaling<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ijk \u2013 image col,row,slice coordinate of finding<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ImageUID \u2013 Image Identifier<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">TopLevel<\/span> <\/span><\/p><ul><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">0 - Series forms one image<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">1 \u2013 A set of Series forms a 4D image (e.g. Dynamic MR)<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">NA \u2013 Series form one image, but is part of a Level 1 4D image<\/span> <\/span><\/p><\/li><\/ul><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">SpacingBetweenSlices \u2013 Scalar Spacing between slices<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">VoxelSpacing \u2013 Vector with x,y,z spacing scalars<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Dim \u2013 Vector with 4D dimensions of the image<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">DCMSerDescr \u2013 The original DICOM Series Description<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">DCMSerUID \u2013 The DICOM Series UID<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">DCMSerNum \u2013 The DICOM Series Number<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">InstanceUIDList \u2013 DICOM Instances that make up this series<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ImageUIDList \u2013 TopLevel-NA Images the make up this Toplevel 1 image<\/span> <\/span><\/p><\/li><\/ul><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">For example, to get the ADC image of Patient ProstateX-0123 do the following. After you imported the DICOM files into your environment, go to patient ProstateX-0123 and find the series with ADC in it. In this case it is \u2018<span>ep2d_diff_tra_DYNDIST_ADC\u2019. It has SeriesNumber 8. The DICOM images in that series form the ADC image for this challenge. Image slice j at coordinate i,j contains a finding fid. See findings for more details. <\/span> <\/span> <\/span><\/p><h3 class=\"western\" id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Findings\"><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Findings<\/span> <\/span><\/h3><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">The findings are documented in the ProstateX-Findings.csv table. Documentation for the columns in that table is as follows:<\/span> <\/span><\/p><ul><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ProxID \u2013 ProstateX patient identifier<\/span> <\/span><\/p><\/li><\/ul><ul><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">fid - Finding ID<\/span> <\/span><\/p><\/li><\/ul><ul><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">pos - Scanner Coordinate position of the finding<\/span> <\/span><\/p><\/li><li><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">ClinSig \u2013 Identifier available in training set that identifies whether this is a clinically significant finding. Either the biopsy GleasonScore was 7 or higher. Findings with a PIRADS score 2 were not biopsied and are not considered clinically significant. In our center the occurrence of clinically significant cancer in PIRADS 2 lesions is less than 5%.<\/span> <\/span><\/p><\/li><\/ul><p><span style=\"color: rgb(0,0,0);\"><span style=\"color: rgb(0,0,0);\"><span style=\"color: rgb(255,0,0);\"><strong>Note<\/strong><\/span>,\u00a0ProxID is the PROSTATEx case ID, and fid is the finding (i.e., lesion) ID in both the ProstateX-Findings.csv file and the ProstateX-Images.csv file. \u00a0The Findings spreadsheet has one row per lesion (if a case has only one lesion, then the only fid for that case will be \u201c1\u201d , alternately if a case has two lesions, then there will be an fid of \u201c1\u201d <strong>and<\/strong> an fid of \u201c2\u201d for that case). \u00a0The Images spreadsheet has a row for every image that contains the lesion - that is why there are multiple rows with the same (ProxID, fid) combination.<\/span><\/span><\/p><div><span style=\"color: rgb(0,0,0);\"> <br\/><\/span><\/div><div><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-PROSTATEx-2\u2014SPIE-AAPM-NCIProstateMRGleasonGradeGroupChallenge(May15,2017toAugust3,2017)\">PROSTATEx-2 \u2014 SPIE-AAPM-NCI Prostate MR Gleason Grade Group Challenge (May 15, 2017 to August 3, 2017)<\/h3><p>The American Association of Physicists in Medicine (AAPM), along with the SPIE (the international society for optics and photonics) and the National Cancer Institute (NCI), conducted a part 2 \u201cGrand Challenge\u201d on the development of quantitative multi-parametric magnetic resonance imaging (MRI) biomarkers for the determination of Gleason Grade Group in prostate cancer. For more details about PROSTATEx-2 please go to <u> <a href=\"http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\/default.asp\" class=\"external-link\" rel=\"nofollow\">http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\/default.asp<\/a> <\/u>.<\/p><p><span style=\"color: rgb(0,0,0);\"> <span style=\"color: rgb(0,0,0);\">Training and test cohorts along with supplemental Ktrans images and lesion information can be obtained separately using the following options for download:<\/span> <br\/><\/span><\/p><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\" class=\"confluenceTh\">Data Type<\/th><th colspan=\"1\" class=\"confluenceTh\"><p>Training Cohort<\/p><p>(112 subjects)<\/p><\/th><th colspan=\"1\" class=\"confluenceTh\"><p>Test Cohort<\/p><p>(70 subjects)<\/p><\/th><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download images (DICOM)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATExChallenge2-v2-doiJNLP.tcia?version=1&amp;modificationDate=1534787028529&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\"><br\/><\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx2-test.tcia?version=1&amp;modificationDate=1534787027933&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download Ktrans images (.mhd)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/app.box.com\/s\/xv6j8yhq4nd7c1eqdn88n1maw3un0xbv\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/app.box.com\/s\/ibue53ch74tst8hd7hknvhw01jxruw2v\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download lesion information (.zip)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateX2-DataInfo-Train.zip?version=1&amp;modificationDate=1494608672116&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\"><span class=\"confluence-link\">\u00a0<\/span><span class=\"confluence-link\">\u00a0<\/span> <\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateX2-DataInfo-Test.zip?version=1&amp;modificationDate=1496674918589&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><p>Download lesion reference thumbnails (.bmp)<\/p><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateXChallenge2ScreenshotsTrain.zip?version=1&amp;modificationDate=1494518725752&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/ProstateXChallenge2ScreenshotsTest.zip?version=1&amp;modificationDate=1496674921348&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p><br\/><\/p><p><span style=\"color: rgb(102,102,102);\">The training set will consist of 112 findings. This dataset will be representative of the technical properties (scanner type, acquisition parameters, file format) and the nature of the prostate lesions of the test set. An associated Excel file will include case name, the coordinates of the centroid of all lesions, and the lesion \u2018truth\u2019 label (Gleason Grade Group). Reference thumbnail images of the lesions will also be provided.<\/span><\/p><p><span style=\"color: rgb(102,102,102);\">The test set will consist of 70 findings. The locations of the lesions will be specified in the accompanying Excel file that will follow the same format as for the training set with the omission of the \u2018truth\u2019 labels. Reference thumbnail images of the lesions will also be provided.<\/span> <strong> <br\/><\/strong><\/p><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <\/colgroup><\/table><\/div><p><strong> <br\/><\/strong><\/p><\/div><\/div><div class=\"tabs-pane \" id=\"23691656a5ea77cf7e964d29ac5f942cc3fc9bb1\" name=\"Citations BITVOODOO_ANDamp; Data Usage Policy\" ><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Citations&amp;DataUsagePolicy\">Citations &amp; Data Usage Policy\u00a0<\/h3><p class=\"auto-cursor-target\">\n<p>\nUsers of this data must abide by the <a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/c4hF\" class=\"external-link\" re=\"nofollow\" rel=\"nofollow\">TCIA Data Usage Policy<\/a> and the <a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">Creative Commons Attribution 3.0 Unported License<\/a> under which it has been published. Attribution should include references to the following citations:\n<\/p><\/p><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Data Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p>Geert Litjens, Oscar Debats, Jelle Barentsz, Nico Karssemeijer, and Henkjan Huisman. &quot;ProstateX Challenge data&quot;, The Cancer Imaging Archive (2017). DOI: <a href=\"https:\/\/doi.org\/10.7937\/K9TCIA.2017.MURS5CL\" class=\"external-link\" rel=\"nofollow\">10.7937\/K9TCIA.2017.MURS5CL<\/a><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Publication Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p>Litjens G, Debats O, Barentsz J, Karssemeijer N, Huisman H. &quot;Computer-aided detection of prostate cancer in MRI&quot;,\u00a0IEEE Transactions on Medical Imaging\u00a02014;33:1083-1092.\u00a0DOI: <a href=\"https:\/\/doi.org\/10.1109\/TMI.2014.2303821\" class=\"external-link\" rel=\"nofollow\">10.1109\/TMI.2014.2303821 <\/a><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">TCIA Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p>Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F.\u00a0<strong>The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository<\/strong>, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1007\/s10278-013-9622-7\" class=\"external-link\" rel=\"nofollow\">10.1007\/s10278-013-9622-7<\/a><\/p><\/div><\/div><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-OtherPublicationsUsingThisData\">Other Publications Using This Data<\/h3><p><span>TCIA maintains<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\" class=\"external-link\" rel=\"nofollow\"> a list of publications<\/a> that leverage our data. <\/span>If you have a publication you'd like to add, please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\" class=\"external-link\" rel=\"nofollow\"> contact the TCIA Helpdesk<\/a>.<\/p><\/div><div class=\"tabs-pane \" id=\"23691656a47beae550a34ad991e9eec3f80a393d\" name=\"Versions\" ><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Version2(Current)2022\/07\/05\">Version 2 (Current) 2022\/07\/05<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup><col\/><col\/><col\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Download images (15.1 GB DICOM)<\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx-v1-doiJNLP.tcia?version=1&amp;modificationDate=1534787029451&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=PROSTATEx\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><\/p><\/div><p class=\"auto-cursor-target\"><span style=\"color: rgb(33,37,41);\">(Download requires<span>\u00a0<\/span><\/span><a style=\"text-decoration: none;text-align: left;\" rel=\"nofollow\" href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a><span style=\"color: rgb(33,37,41);\">)<\/span><\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\">Ktrans images (.mhd) and Lesion Info (.csv)<\/td><td class=\"confluenceTd\">See Detailed Description tab<\/td><td class=\"confluenceTd\"><br\/><\/td><\/tr><tr><td class=\"confluenceTd\">Test set reference standard (csv)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/pages\/viewpage.action?pageId=23691656&amp;preview=%2F23691656%2F127665000%2FProstateX-Findings-Test.csv\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p class=\"auto-cursor-target\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>Added Test Reference Standard document<\/p><h3 id=\"SPIEAAPMNCIPROSTATExChallenges(PROSTATEx)-Version1:Updated2017\/03\/29\">Version 1: Updated 2017\/03\/29<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\" class=\"confluenceTh\">Data Type<\/th><th colspan=\"1\" class=\"confluenceTh\">Download all or Query\/Filter<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Download images (15.1 GB DICOM)<\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/23691656\/PROSTATEx-v1-doiJNLP.jnlp?version=1&amp;modificationDate=1490928917140&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/public.cancerimagingarchive.net\/ncia\/externalLinks.jsf?collectionName=PROSTATEx\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\">\u00a0<\/span>\u00a0<a href=\"https:\/\/public.cancerimagingarchive.net\/ncia\/externalLinks.jsf?collectionName=PROSTATEx\" class=\"external-link\" rel=\"nofollow\">\u00a0<\/a><span class=\"confluence-link\"><br\/><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><\/div><div class=\"tabs-pane \" id=\"23691656b6a68cb843e0491a8e56d80d1e46f164\" name=\"Publications that Leveraged this Dataset\" ><p><iframe class=\"airtable-embed\" src=\"https:\/\/airtable.com\/embed\/shrIUQYW4LQU8WvFu?backgroundColor=purple&layout=card\" frameborder=\"0\" onmousewheel=\"\" width=\"100%\" height=\"533\" style=\"background: transparent; border: 1px solid #ccc;\"><\/iframe><\/p><\/div><\/div><\/div><\/div><\/div>\n<\/div>\n<div class=\"cell aside\" data-type=\"aside\">\n<div class=\"innerCell\">\n<p><br\/><\/p><\/div>\n<\/div>\n<\/div>\n<\/div>","versions":false,"additional_resources":"The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.\n \n<ul><li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=prostatex\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li><\/ul>","cancer_locations":["Prostate"],"collection_page_accessibility":"Public","publications_related":"","version_change_log":"","version_change_log_archived":"","analysis_results":"TCIA encourages the community to\u00a0<a href=\"http:\/\/www.cancerimagingarchive.net\/analysis-results\/\">publish your analyses of our datasets<\/a>. Below is a list of such third party analyses published using this Collection:\n<ul><li><a href=\"https:\/\/doi.org\/10.7937\/TCIA.2019.DEG7ZG1U\">High Resolution Prostate Segmentations for the ProstateX-Challenge<\/a>\u00a0<\/li><li><a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/oaAvB\">PROSTATEx Zone Segmentations<\/a><\/li><\/ul>","collection_status":"Complete","publications_using":"TCIA maintains<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\"> a list of publications<\/a> that leverage our data. If you have a publication you'd like to add, please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\"> contact the TCIA Helpdesk<\/a>.","species":["Human"],"collection_title":"SPIE-AAPM-NCI PROSTATEx Challenges","detailed_description":"<h3>PROSTATEx Challenge (November 21, 2016 to February 16, 2017)<\/h3>\nSPIE, along with the support of the American Association of Physicists in Medicine (AAPM) and the National Cancer Institute (NCI), conducted a \u201cGrand Challenge\u201d on quantitative image analysis methods for the diagnostic classification of clinically significant prostate lesions. \u00a0For more details, go to\u00a0<a href=\"https:\/\/prostatex.grand-challenge.org\/\">https:\/\/prostatex.grand-challenge.org\/<\/a>\u00a0.\u00a0\u00a0\n Training and test cohorts along with supplemental Ktrans images and lesion information can be obtained separately using the following options for download:\n<table><colgroup> <col\/> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\">Data Type<\/th><th colspan=\"1\"><p>Training Cohort<\/p><p>(204 subjects)<\/p><\/th><th colspan=\"1\"><p>Test Cohort<\/p><p>(140 subjects)<\/p><\/th><\/tr><tr><td colspan=\"1\"><p>Download images (DICOM)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/PROSTATEx-train.tcia\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<br\/><\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/PROSTATEx-test.tcia\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download Ktrans images (.mhd)<\/p><\/td><td colspan=\"1\"><div><p>\n<a href=\"https:\/\/app.box.com\/s\/y871i386j4o9rqwcsms5mqni63nojzx1\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a href=\"https:\/\/app.box.com\/s\/k3iofc0r3ktjnb4f7105lssdzjon95ie\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download lesion information (.zip)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateX-TrainingLesionInformationv2.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateX-TestLesionInformation.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download lesion reference thumbnails (.bmp)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateX-Screenshots-Train.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a href=\"https:\/\/app.box.com\/s\/7jn4jtd3pbi9rlurc4pvnkx554lnfljw\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><\/tbody><\/table>\nThe images come in two encodings. The acquired MR is provided in DICOM encoding. Additionally Ktrans images are provided. They come in mhd format. Ktrans is a key pharmacokinetic parameter computed from the available Dynamic contrast enhanced T1-weighted series. Each patient has one study with several DICOM images and one Ktrans image. The Ktrans image is encoded in two files ProstateX-[ProxID]-Ktrans.[mhd\/zraw], where ProxID is the ProstateX patient identifier. The DICOM images comprise several Series each comprising several Instances. The DICOM files are documented in the ProstateX-Images.csv file. The columns in that file encode the following:\n<ul><li><p> ProxID \u2013 ProstateX patient identifier. <\/p><\/li><li><p> Name \u2013 Series Description <\/p><\/li><li><p> Studydate \u2013 Study Date <\/p><\/li><li><p> fid \u2013 Finding ID <\/p><\/li><li><p> Pos \u2013 Scanner Coordinate position of the finding <\/p><\/li><li><p> WorldMatrix \u2013 Matrix describing image orientation and scaling <\/p><\/li><li><p> ijk \u2013 image col,row,slice coordinate of finding <\/p><\/li><li><p> ImageUID \u2013 Image Identifier <\/p><\/li><li><p> TopLevel <\/p><ul><li><p> 0 - Series forms one image <\/p><\/li><li><p> 1 \u2013 A set of Series forms a 4D image (e.g. Dynamic MR) <\/p><\/li><li><p> NA \u2013 Series form one image, but is part of a Level 1 4D image <\/p><\/li><\/ul><\/li><li><p> SpacingBetweenSlices \u2013 Scalar Spacing between slices <\/p><\/li><li><p> VoxelSpacing \u2013 Vector with x,y,z spacing scalars <\/p><\/li><li><p> Dim \u2013 Vector with 4D dimensions of the image <\/p><\/li><li><p> DCMSerDescr \u2013 The original DICOM Series Description <\/p><\/li><li><p> DCMSerUID \u2013 The DICOM Series UID <\/p><\/li><li><p> DCMSerNum \u2013 The DICOM Series Number <\/p><\/li><li><p> InstanceUIDList \u2013 DICOM Instances that make up this series <\/p><\/li><li><p> ImageUIDList \u2013 TopLevel-NA Images the make up this Toplevel 1 image <\/p><\/li><\/ul>\nFor example, to get the ADC image of Patient ProstateX-0123 do the following. After you imported the DICOM files into your environment, go to patient ProstateX-0123 and find the series with ADC in it. In this case it is \u2018ep2d_diff_tra_DYNDIST_ADC\u2019. It has SeriesNumber 8. The DICOM images in that series form the ADC image for this challenge. Image slice j at coordinate i,j contains a finding fid. See findings for more details.  \n<h3> Findings <\/h3>\nThe findings are documented in the ProstateX-Findings.csv table. Documentation for the columns in that table is as follows:\n<ul><li><p> ProxID \u2013 ProstateX patient identifier <\/p><\/li><\/ul>\n<ul><li><p> fid - Finding ID <\/p><\/li><\/ul>\n<ul><li><p> pos - Scanner Coordinate position of the finding <\/p><\/li><li><p> ClinSig \u2013 Identifier available in training set that identifies whether this is a clinically significant finding. Either the biopsy GleasonScore was 7 or higher. Findings with a PIRADS score 2 were not biopsied and are not considered clinically significant. In our center the occurrence of clinically significant cancer in PIRADS 2 lesions is less than 5%. <\/p><\/li><\/ul>\n<strong>Note<\/strong>,\u00a0ProxID is the PROSTATEx case ID, and fid is the finding (i.e., lesion) ID in both the ProstateX-Findings.csv file and the ProstateX-Images.csv file. \u00a0The Findings spreadsheet has one row per lesion (if a case has only one lesion, then the only fid for that case will be \u201c1\u201d , alternately if a case has two lesions, then there will be an fid of \u201c1\u201d <strong>and<\/strong> an fid of \u201c2\u201d for that case). \u00a0The Images spreadsheet has a row for every image that contains the lesion - that is why there are multiple rows with the same (ProxID, fid) combination.\n <br\/>\n<h3>PROSTATEx-2 \u2014 SPIE-AAPM-NCI Prostate MR Gleason Grade Group Challenge (May 15, 2017 to August 3, 2017)<\/h3><p>The American Association of Physicists in Medicine (AAPM), along with the SPIE (the international society for optics and photonics) and the National Cancer Institute (NCI), conducted a part 2 \u201cGrand Challenge\u201d on the development of quantitative multi-parametric magnetic resonance imaging (MRI) biomarkers for the determination of Gleason Grade Group in prostate cancer. For more details about PROSTATEx-2 please go to <u> <a href=\"http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\/default.asp\">http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\/default.asp<\/a> <\/u>.<\/p><p> Training and test cohorts along with supplemental Ktrans images and lesion information can be obtained separately using the following options for download: <br\/><\/p><div><table><colgroup> <col\/> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\">Data Type<\/th><th colspan=\"1\"><p>Training Cohort<\/p><p>(112 subjects)<\/p><\/th><th colspan=\"1\"><p>Test Cohort<\/p><p>(70 subjects)<\/p><\/th><\/tr><tr><td colspan=\"1\"><p>Download images (DICOM)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/PROSTATExChallenge2-v2-doiJNLP.tcia\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<br\/><\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/PROSTATEx2-test.tcia\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download Ktrans images (.mhd)<\/p><\/td><td colspan=\"1\"><div><p>\n<a href=\"https:\/\/app.box.com\/s\/xv6j8yhq4nd7c1eqdn88n1maw3un0xbv\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a href=\"https:\/\/app.box.com\/s\/ibue53ch74tst8hd7hknvhw01jxruw2v\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download lesion information (.zip)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateX2-DataInfo-Train.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n\u00a0\u00a0 <\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateX2-DataInfo-Test.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\"><p>Download lesion reference thumbnails (.bmp)<\/p><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateXChallenge2ScreenshotsTrain.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><td colspan=\"1\"><div><p>\n<a download=\"\" href=\"\/wp-content\/uploads\/ProstateXChallenge2ScreenshotsTest.zip\" target=\"_blank\"><button><i> <\/i> Download<\/button><\/a>\u00a0\n<\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>The training set will consist of 112 findings. This dataset will be representative of the technical properties (scanner type, acquisition parameters, file format) and the nature of the prostate lesions of the test set. An associated Excel file will include case name, the coordinates of the centroid of all lesions, and the lesion \u2018truth\u2019 label (Gleason Grade Group). Reference thumbnail images of the lesions will also be provided.<\/p><p>The test set will consist of 70 findings. The locations of the lesions will be specified in the accompanying Excel file that will follow the same format as for the training set with the omission of the \u2018truth\u2019 labels. Reference thumbnail images of the lesions will also be provided. <strong> <br\/><\/strong><\/p><div><table><colgroup> <col\/> <col\/> <\/colgroup><\/table><\/div><p><strong> <br\/><\/strong><\/p>","related_analysis_results":false,"subjects":"346","collection_short_title":"PROSTATEx","data_types":["MR"],"date_updated":"2023-09-13","collection_browse_title":"","supporting_data":["Image Analyses"],"collection_featured_image":{"ID":"8230","post_author":"6","post_date":"2023-09-13 04:00:43","post_date_gmt":"2023-09-13 04:00:43","post_content":"","post_title":"image2016-10-6-14627","post_excerpt":"","post_status":"inherit","comment_status":"open","ping_status":"closed","post_password":"","post_name":"image2016-10-6-14627","to_ping":"","pinged":"","post_modified":"2023-09-13 12:03:20","post_modified_gmt":"2023-09-13 12:03:20","post_content_filtered":"","post_parent":"5691","guid":"https:\/\/cm.vastapps.dev\/wp-content\/uploads\/image2016-10-6-14627.png","menu_order":"0","post_type":"attachment","post_mime_type":"image\/png","comment_count":"0","pod_item_id":"8230"},"collection_summary":"PROSTATEx has been superseded by PI-CAI <div><p>The ProstateX dataset (both training and testing cases) have been included in the PI-CAI Public Training and Development dataset. As such, ProstateX as a benchmark has been deprecated and is superseded by the PI-CAI challenge. PI-CAI is an all-new grand challenge, with over 10,000 carefully-curated prostate MRI exams to validate modern AI algorithms and estimate radiologists' performance at clinically significant prostate cancer detection and diagnosis. Key aspects of the study design have been established in conjunction with an international, multi-disciplinary scientific advisory board (16 experts in prostate AI, radiology and urology)\u00a0 - to unify and standardize present-day guidelines, and to ensure meaningful validation of prostate-AI towards clinical translation. Please refer to <a href=\"https:\/\/pi-cai.grand-challenge.org\">https:\/\/pi-cai.grand-challenge.org<\/a> for more information.<\/p><\/div>\n<br\/>This collection is a retrospective set of prostate MR studies. All studies included T2-weighted (T2W), proton density-weighted (PD-W), dynamic contrast enhanced (DCE), and diffusion-weighted (DW) imaging. The images were acquired on two different types of Siemens 3T MR scanners, the MAGNETOM Trio and Skyra. T2-weighted images were acquired using a turbo spin echo sequence and had a resolution of around 0.5 mm in plane and a slice thickness of 3.6 mm. The DCE time series was acquired using a 3-D turbo flash gradient echo sequence with a resolution of around 1.5 mm in-plane, a slice thickness of 4 mm and a temporal resolution of 3.5 s. The proton density weighted image was acquired prior to the DCE time series using the same sequence with different echo and repetition times and a different flip angle. Finally, the DWI series were acquired with a single-shot echo planar imaging sequence with a resolution of 2 mm in-plane and 3.6 mm slice thickness and with diffusion-encoding gradients in three directions. Three b-values were acquired (50, 400, and 800), and subsequently, the ADC map was calculated by the scanner software. All images were acquired without an endorectal coil.\n<h3>Accessing the PROSTATEx Challenge Data Sets<\/h3>\nThe PROSTATEx Challenge (\" SPIE-AAPM-NCI Prostate MR Classification Challenge\u201d) focused on\u00a0 quantitative image analysis methods for the diagnostic classification of clinically significant prostate cancers and was held in conjunction with the 2017 SPIE Medical Imaging Symposium. \u00a0PROSTATEx ran from November 21, 2016 to January 15, 2017, though a\u00a0\"live\" version has also been established at\u00a0<a href=\"https:\/\/prostatex.grand-challenge.org\">https:\/\/prostatex.grand-challenge.org<\/a>  \u00a0which serves as an ongoing way for researchers to benchmark their performance for this task. \nThe PROSTATEx-2 Challenge (\" SPIE-AAPM-NCI\u00a0 Prostate MR Gleason Grade Group Challenge\" ) ran from May 15, 2017 to June 23, 2017 and\u00a0was focused on\u00a0 the development of quantitative multi-parametric MRI biomarkers for the determination of Gleason Grade Group in prostate cancer.\u00a0 It was\u00a0 held in conjunction with the 2017 AAPM Annual Meeting (see\u00a0 <a href=\"http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2\">http:\/\/www.aapm.org\/GrandChallenge\/PROSTATEx-2<\/a> ) .\u00a0\nSupplemental data and instructions specific to both challenges can be found on the Detailed Description tab below.\u00a0\u00a0 <br\/>","collection_acknowledgements":"The prostate MR imaging was performed at the Radboud University Medical Centre (Radboudumc) in the Prostate MR Reference Center under supervision of prof. Dr. Barentsz. The Radboudumc is located in Nijmegen, The Netherlands. The dataset was collected and curated for research in computer aided diagnosis of prostate MR under supervision of Dr. Huisman, Radboudumc.\n\n<div class=\"cm-content-image\"><a href=\"\/wp-content\/uploads\/PROSTATEx-2_logo.jpg\" rel=\"prettyPhoto noopener\" target=\"_blank\"><img src=\"\/wp-content\/uploads\/PROSTATEx-2_logo.jpg\"\/><\/a><\/div>","collection_funding":"","hide_from_browse_table":[],"_links":{"self":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections\/5691"}],"collection":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections"}],"about":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/types\/tcia_collection"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media\/8230"}],"wp:attachment":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media?parent=5691"}],"wp:term":[{"taxonomy":"tcia_citation_tax","embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/v1\/citation-tax?post=5691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}