{"id":5672,"date":"2023-09-04T03:16:55","date_gmt":"2023-09-04T03:16:55","guid":{"rendered":"https:\/\/cm.vastapps.dev\/tcia-collection\/rembrandt\/"},"modified":"2023-09-13T12:02:26","modified_gmt":"2023-09-13T12:02:26","slug":"rembrandt","status":"publish","type":"tcia_collection","link":"https:\/\/cm.vastapps.dev\/tcia-collection\/rembrandt\/","title":{"rendered":"REMBRANDT"},"featured_media":0,"template":"","citation-tax":[],"cancer_types":["Low &amp; High Grade Glioma"],"citations":[4610,2925],"collection_doi":"10.7937\/K9\/TCIA.2015.588OZUZB","collection_download_info":"Summary\nFinding better therapies for the treatment of brain tumors is hampered by the lack of consistently obtained molecular data in a large sample set and the ability to integrate biomedical data from disparate sources enabling translation of therapies from bench to bedside. Hence, a critical factor in the advancement of biomedical research and clinical translation is the ease with which data can be integrated, redistributed, and analyzed both within and across functional domains. Novel biomedical informatics infrastructure and tools are essential for developing individualized patient treatment based on the specific genomic signatures in each patient's tumor. The Repository of Molecular Brain Neoplasia Data (REMBRANDT) is aimed at facilitating discovery by connecting the dots between clinical information and genomic characterization data. <br\/>\nREMBRANDT contains data generated through the Glioma Molecular Diagnostic Initiative from 874 glioma specimens comprising approximately 566 gene expression arrays, 834 copy number arrays, and 13,472 clinical phenotype data points. These data are currently housed in <u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\">Georgetown University's G-DOC System<\/a> <\/u> and are described in a <u> <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19208739\">related manuscript<\/a> <\/u>. \u00a0This image collection was created as a companion data set to augment the larger\u00a0REMBRANDT\u00a0project. It contains the pre-surgical magnetic resonance (MR) multi-sequence images from 130 REMBRANDT patients.\u00a0\n<br\/>","collection_downloads":[5222,5223,5224,5225],"full_export":"<p><span style=\"font-size: 20.0px;font-weight: bold;line-height: 1.5;\">Summary<\/span><\/p><span style=\"color: rgb(0,0,0);\">Finding better therapies for the treatment of brain tumors is hampered by the lack of consistently obtained molecular data in a large sample set and the ability to integrate biomedical data from disparate sources enabling translation of therapies from bench to bedside. Hence, a critical factor in the advancement of biomedical research and clinical translation is the ease with which data can be integrated, redistributed, and analyzed both within and across functional domains. Novel biomedical informatics infrastructure and tools are essential for developing individualized patient treatment based on the specific genomic signatures in each patient's tumor. The Repository of Molecular Brain Neoplasia Data (REMBRANDT) is aimed at facilitating discovery by connecting the dots between clinical information and genomic characterization data. <br\/><\/span><p><span style=\"color: rgb(0,0,0);\">REMBRANDT contains data generated through the Glioma Molecular Diagnostic Initiative from 874 glioma specimens comprising approximately 566 gene expression arrays, 834 copy number arrays, and 13,472 clinical phenotype data points. These data are currently housed in <u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\" class=\"external-link\" rel=\"nofollow\">Georgetown University's G-DOC System<\/a> <\/u> and are described in a <u> <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19208739\" class=\"external-link\" rel=\"nofollow\">related manuscript<\/a> <\/u>. \u00a0<\/span>This image collection was created as a companion data set to augment the larger\u00a0REMBRANDT\u00a0project. It contains the pre-surgical magnetic resonance (MR) multi-sequence images from 130 REMBRANDT patients.\u00a0<\/p><p><br\/><\/p><div class=\"tab-style-builtin\"><div class=\"localtabs-macro\"><div class=\"aui-tabs horizontal-tabs\" role=\"application\" data-aui-responsive=\"true\"><ul class=\"tabs-menu\"><li class=\"menu-item bv-localtab  active-tab \"><a href=\"#35392295325d057f3d947b081c4fb0f2de9ff25\"><strong>Data Access<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#3539229a54d9e15dc7742539676fa33cf65b390\"><strong>Detailed Description<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#3539229961eb9e8e95945abac523cb7c2408369\"><strong>Citations &amp; Data Usage Policy<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#3539229da36b6aa791f43e4afad2a9ab2525a71\"><strong>Versions<\/strong><\/a> <\/li><\/ul><div class=\"tabs-pane  active-pane \" id=\"35392295325d057f3d947b081c4fb0f2de9ff25\" active=\"true\" name=\"Data Access\" ><h3 id=\"REMBRANDT-DataAccess\">Data Access<\/h3><p class=\"auto-cursor-target\">\nSome data in this collection contains images that could potentially be used to reconstruct a human face.  To safeguard the privacy of participants, users must sign and submit a <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/4556915\/TCIA%20Restricted%20License%2020220519.pdf?version=1&amp;modificationDate=1652964581655&amp;api=v2\" class=\"external-link\" rel=\"nofollow\">TCIA Restricted License Agreement<\/a> to <a href=\"mailto:help@cancerimagingarchive.net\" class=\"external-link\" rel=\"nofollow\">help@cancerimagingarchive.net<\/a> before accessing the data.<\/p><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 63.9163%;\"><colgroup><col style=\"width: 28.5624%;\"\/><col style=\"width: 44.4015%;\"\/><col style=\"width: 26.9693%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\">Images (DICOM, 9.9GB)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/TCIA_REMBRANDT_06-22-2015.tcia?version=1&amp;modificationDate=1534787409774&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=REMBRANDT\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><br\/><\/p><p>(Download requires <a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/4556915\/TCIA%20Restricted%20License%2020220519.pdf?version=1&amp;modificationDate=1652964581655&amp;api=v2\" class=\"external-link\" rel=\"nofollow\">TCIA Restricted<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\">Clinical Data (XLS)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/clinical_2014-01-16.xlsx?version=2&amp;modificationDate=1629237658680&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\"><span style=\"color: rgb(0,51,102);\"> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MR_featurekey4.pdf?version=1&amp;modificationDate=1319831391198&amp;api=v2\" rel=\"nofollow\"> <span style=\"color: rgb(0,51,102);\">VASARI_MR_featurekey4<\/span> <\/a> <\/span> (pdf)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MR_featurekey4.pdf?version=1&amp;modificationDate=1319831391198&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\"><span style=\"color: rgb(0,51,102);\"> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MRI_features%20%28gmdi%20-%20wiki%29.xls?version=2&amp;modificationDate=1366145660931&amp;api=v2\" rel=\"nofollow\"> <span style=\"color: rgb(0,51,102);\">VASARI_MRI_features (gmdi-wiki)<\/span> <\/a> <\/span>(XLS)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MRI_features%20%28gmdi%20-%20wiki%29.xls?version=2&amp;modificationDate=1366145660931&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>Click the Versions tab for more info about data releases.<\/p><h3 style=\"text-align: left;\" id=\"REMBRANDT-AdditionalResourcesforthisDataset\">Additional Resources for this Dataset<\/h3><p>The following external resources are also available.\u00a0 These are not hosted or supported by TCIA, but may be useful to researchers utilizing this collection.<\/p><ul><li class=\"xmsonormal\" style=\"text-align: left;\"><a href=\"https:\/\/gdoc.georgetown.edu\/\" class=\"external-link\" rel=\"nofollow\"><span>Molecular\/Clinical Data in <\/span>G-DOC<\/a><\/li><li class=\"xmsonormal\" style=\"text-align: left;\"><p class=\"condensed\"><a href=\"https:\/\/dx.doi.org\/10.25790\/bml0cm.87\" class=\"external-link\" rel=\"nofollow\">Segmentation Labels for the REMBRANDT brain cancer MRI image collection<\/a> are available on NITRC and are described in this <a href=\"https:\/\/doi.org\/10.1038\/s41597-022-01415-1\" class=\"external-link\" rel=\"nofollow\">Nature Scientific Data publication<\/a><\/p><\/li><\/ul><\/div><div class=\"tabs-pane \" id=\"3539229a54d9e15dc7742539676fa33cf65b390\" name=\"Detailed Description\" ><h3 id=\"REMBRANDT-DetailedDescription\">Detailed Description<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><tbody><tr><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p>Collection Statistics<\/p><\/div><\/th><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p>Updated 09\/12\/2014<\/p><\/div><\/th><\/tr><tr><td class=\"confluenceTd\"><p>Modalities<\/p><\/td><td class=\"confluenceTd\"><p>MR<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Participants<\/p><\/td><td class=\"confluenceTd\"><p>130<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Studies<\/p><\/td><td class=\"confluenceTd\"><p>174<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Series<\/p><\/td><td class=\"confluenceTd\"><p>1,483<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Images<\/p><\/td><td class=\"confluenceTd\"><p>110,020<\/p><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\">Image Size (GB)<\/td><td colspan=\"1\" class=\"confluenceTd\">9.9<\/td><\/tr><\/tbody><\/table><\/div><p><br\/><\/p><h3 id=\"REMBRANDT-ClinicalandGenomicsData\">Clinical and Genomics Data<\/h3><p><span>A <\/span> <u> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/clinical_2014-01-16.xlsx?version=1&amp;modificationDate=1389900784210&amp;api=v2\" rel=\"nofollow\">clinical data dump<\/a> <\/u> <span> was<\/span> <span> exported from the publicly accessible section of the\u00a0REMBRANDT Data Portal\u00a0on 1\/16\/2014 for convenience to TCIA users. The old data portal has since been retired and all non-image data has been migrated to <u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\" class=\"external-link\" rel=\"nofollow\">Georgetown University's G-DOC System<\/a> <\/u>.<\/span><\/p><p><u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\" class=\"external-link\" rel=\"nofollow\">G-DOC<\/a> <\/u> contains extensive clinical, gene, and expression data of the same cases to research the link between radiological phenotype and tissue genotype. Registration is required. After logging in search for the REMBRANDT study to locate the data. T<span>he mapping table they provide within G-DOC is required to match TCIA's subject identifiers to the G-DOC identifiers.<\/span><\/p><h3 id=\"REMBRANDT-RadiologistAnalyses\">Radiologist Analyses<\/h3><p>In addition, there are imaging feature characterizations provided by neuroradiologists from Thomas Jefferson University (TJU) Hospital. This feature set has become known as &quot;VASARI&quot; and became the starting point for the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/pages\/viewpage.action?pageId=1966530\">The Cancer Genome Archive (TCGA) Glioma Phenotype Research Group<\/a>\u00a0efforts, which is utilizing data from the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/pages\/viewpage.action?pageId=1966258\">TCGA-GBM<\/a>\u00a0and\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/pages\/viewpage.action?pageId=5309188\">TCGA-LGG<\/a>\u00a0collections.<\/p><ul><li><a style=\"line-height: 1.42857;\" href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MR_featurekey4.pdf?version=1&amp;modificationDate=1319831391198&amp;api=v2\" rel=\"nofollow\">VASARI_MR_featurekey4.pdf<\/a>- This document is a &quot;key&quot; for understanding and interpreting the annotation spreadsheet.<\/li><li><a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MRI_features%20%28gmdi%20-%20wiki%29.xls?version=2&amp;modificationDate=1366145660931&amp;api=v2\" rel=\"nofollow\">VASARI_MRI_features (gmdi-wiki).xls<\/a>- This document is the actual annotations spreadsheet generated at TJU.<\/li><\/ul><p><br\/><\/p><\/div><div class=\"tabs-pane \" id=\"3539229961eb9e8e95945abac523cb7c2408369\" name=\"Citations BITVOODOO_ANDamp; Data Usage Policy\" ><h3 id=\"REMBRANDT-Citations&amp;DataUsagePolicy\">Citations &amp; Data Usage Policy\u00a0<\/h3><p class=\"auto-cursor-target\">\n<p>\nUsers must abide by the <a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/c4hF\" class=\"external-link\" rel=\"nofollow\">TCIA Data Usage Policy and Restrictions<\/a>. Attribution should include references to the following citations:\n<\/p><\/p><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Data Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p><span style=\"color: rgb(102,102,102);letter-spacing: 0.0px;\">Scarpace, L., Flanders, A. E., Jain, R., Mikkelsen, T., &amp; Andrews, D. W. (2019). <\/span><strong style=\"color: rgb(102,102,102);letter-spacing: 0.0px;\">Data From REMBRANDT [Data set].<\/strong><span style=\"color: rgb(102,102,102);letter-spacing: 0.0px;\"> The Cancer Imaging Archive. <\/span><a style=\"letter-spacing: 0.0px;\" href=\"https:\/\/doi.org\/10.7937\/K9\/TCIA.2015.588OZUZB\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.7937\/K9\/TCIA.2015.588OZUZB<\/a><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">TCIA Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p><span style=\"color: rgb(102,102,102);letter-spacing: 0.0px;\">Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., &amp; Prior, F. (2013). <strong>The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository.<\/strong> Journal of Digital Imaging, 26(6), 1045\u20131057. <\/span><a style=\"letter-spacing: 0.0px;\" href=\"https:\/\/doi.org\/10.1007\/s10278-013-9622-7\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.1007\/s10278-013-9622-7<\/a><\/p><\/div><\/div><h3 id=\"REMBRANDT-OtherPublicationsUsingThisData\">Other Publications Using This Data<\/h3><p>TCIA maintains <a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\" class=\"external-link\" rel=\"nofollow\">a list of publications<\/a> which leverage our data. If you have a publication you'd like to add please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\" class=\"external-link\" rel=\"nofollow\"> contact TCIA's Helpdesk<\/a>.<\/p><\/div><div class=\"tabs-pane \" id=\"3539229da36b6aa791f43e4afad2a9ab2525a71\" name=\"Versions\" ><h3 id=\"REMBRANDT-Version2(Current)2021\/08\/17\">Version 2(Current) 2021\/08\/17<\/h3><p>Some rows in the Clinical Data file were found to be misaligned per column headers:\u00a0<\/p><p>row 39,87,93,104: right shift by one (change within\u00a0MRI findings or OnStudy Therapy Chemo Agent Name)<br\/>row 46,57: right shift by 2 (change within MRI Findings)<\/p><p>these realign CSV with no further adjustments made to content.<\/p><h3 id=\"REMBRANDT-Version1:Updated2014\/09\/12\">Version 1 : Updated 2014\/09\/12<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\" class=\"confluenceTh\">Data Type<\/th><th colspan=\"1\" class=\"confluenceTh\">Download all or Query\/Filter<\/th><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\">Images (DICOM, <span>9.9<\/span>GB)<\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/TCIA_REMBRANDT_06-22-2015.tcia?version=1&amp;modificationDate=1534787409774&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=REMBRANDT\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span>\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=REMBRANDT\" class=\"external-link\" rel=\"nofollow\">\u00a0<\/a><\/p><p><span>Downloads require the <\/span> <a rel=\"nofollow\" href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a> <span>.<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><span>Clinical Data (XLS)<\/span><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/clinical_2014-01-16.xlsx?version=2&amp;modificationDate=1629237658680&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><span style=\"color: rgb(0,51,102);\"> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MR_featurekey4.pdf?version=1&amp;modificationDate=1319831391198&amp;api=v2\" rel=\"nofollow\"> <span style=\"color: rgb(0,51,102);\">VASARI_MR_featurekey4<\/span> <\/a> <\/span> <span> (pdf)<\/span><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MR_featurekey4.pdf?version=1&amp;modificationDate=1319831391198&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\"><span style=\"color: rgb(0,51,102);\"> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MRI_features%20%28gmdi%20-%20wiki%29.xls?version=2&amp;modificationDate=1366145660931&amp;api=v2\" rel=\"nofollow\"> <span style=\"color: rgb(0,51,102);\">VASARI_MRI_features (gmdi-wiki)<\/span> <\/a> <\/span> <span>(XLS)<\/span><\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/3539229\/VASARI_MRI_features%20%28gmdi%20-%20wiki%29.xls?version=2&amp;modificationDate=1366145660931&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/div><\/div><p><br\/><\/p>","versions":false,"additional_resources":"The following external resources are also available.\u00a0 These are not hosted or supported by TCIA, but may be useful to researchers utilizing this collection.\n<ul><li><a href=\"https:\/\/gdoc.georgetown.edu\/\">Molecular\/Clinical Data in G-DOC<\/a><\/li><li><p><a href=\"https:\/\/dx.doi.org\/10.25790\/bml0cm.87\">Segmentation Labels for the REMBRANDT brain cancer MRI image collection<\/a> are available on NITRC and are described in this <a href=\"https:\/\/doi.org\/10.1038\/s41597-022-01415-1\">Nature Scientific Data publication<\/a><\/p><\/li><\/ul>","cancer_locations":["Brain"],"collection_page_accessibility":"Public","publications_related":"","version_change_log":"","version_change_log_archived":"","analysis_results":"","collection_status":"Complete","publications_using":"TCIA maintains <a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\">a list of publications<\/a> which leverage our data. If you have a publication you'd like to add please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\"> contact TCIA's Helpdesk<\/a>.","species":["Human"],"collection_title":"REMBRANDT","detailed_description":"<br\/>\n<h3>Clinical and Genomics Data<\/h3>\nA  <u> <a download=\"\" href=\"\/wp-content\/uploads\/clinical_2014-01-16.xlsx\" target=\"_blank\">clinical data dump<\/a> <\/u>  was  exported from the publicly accessible section of the\u00a0REMBRANDT Data Portal\u00a0on 1\/16\/2014 for convenience to TCIA users. The old data portal has since been retired and all non-image data has been migrated to <u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\">Georgetown University's G-DOC System<\/a> <\/u>.\n<u> <a href=\"https:\/\/gdoc.georgetown.edu\/gdoc\">G-DOC<\/a> <\/u> contains extensive clinical, gene, and expression data of the same cases to research the link between radiological phenotype and tissue genotype. Registration is required. After logging in search for the REMBRANDT study to locate the data. The mapping table they provide within G-DOC is required to match TCIA's subject identifiers to the G-DOC identifiers.\n<h3>Radiologist Analyses<\/h3>\nIn addition, there are imaging feature characterizations provided by neuroradiologists from Thomas Jefferson University (TJU) Hospital. This feature set has become known as \"VASARI\" and became the starting point for the\u00a0<a href=\"\/display\/Public\/TCGA+Glioma+Phenotype+Research+Group\">The Cancer Genome Archive (TCGA) Glioma Phenotype Research Group<\/a>\u00a0efforts, which is utilizing data from the\u00a0<a href=\"\/pages\/viewpage.action?pageId=1966258\">TCGA-GBM<\/a>\u00a0and\u00a0<a href=\"\/pages\/viewpage.action?pageId=5309188\">TCGA-LGG<\/a>\u00a0collections.\n<ul><li><a download=\"\" href=\"\/wp-content\/uploads\/VASARI_MR_featurekey4.pdf\" target=\"_blank\">VASARI_MR_featurekey4.pdf<\/a>- This document is a \"key\" for understanding and interpreting the annotation spreadsheet.<\/li><li><a download=\"\" href=\"\/wp-content\/uploads\/VASARI_MRI_features-gmdi-wiki.xls\" target=\"_blank\">VASARI_MRI_features (gmdi-wiki).xls<\/a>- This document is the actual annotations spreadsheet generated at TJU.<\/li><\/ul>\n<br\/>","related_analysis_results":false,"subjects":"130","collection_short_title":"REMBRANDT","data_types":["MR"],"date_updated":"2023-09-13","collection_browse_title":"","supporting_data":["Clinical","Genomics","Image Analyses"],"collection_featured_image":false,"collection_summary":"","collection_acknowledgements":"","collection_funding":"","hide_from_browse_table":[],"_links":{"self":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections\/5672"}],"collection":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections"}],"about":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/types\/tcia_collection"}],"wp:attachment":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media?parent=5672"}],"wp:term":[{"taxonomy":"tcia_citation_tax","embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/v1\/citation-tax?post=5672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}