{"id":5629,"date":"2023-09-04T03:13:49","date_gmt":"2023-09-04T03:13:49","guid":{"rendered":"https:\/\/cm.vastapps.dev\/tcia-collection\/mouse-astrocytoma\/"},"modified":"2023-09-13T12:00:34","modified_gmt":"2023-09-13T12:00:34","slug":"mouse-astrocytoma","status":"publish","type":"tcia_collection","link":"https:\/\/cm.vastapps.dev\/tcia-collection\/mouse-astrocytoma\/","title":{"rendered":"MOUSE-ASTROCYTOMA"},"featured_media":0,"template":"","citation-tax":[],"cancer_types":["Glioblastoma Multiforme"],"citations":[4534,2925],"collection_doi":"10.7937\/K9TCIA.2017.SGW7CAQW","collection_download_info":"Click the Versions tab for more info about data releases.","collection_downloads":[5126],"full_export":"<h2 id=\"MouseAstrocytoma-Summary\">Summary<\/h2><p>This collection consists of magnetic resonance images (MRI) of genetically engineered mouse models (GEMMs) of high grade astrocytoma, including glioblastoma multiforme (GBM).<\/p><p>In these GEMMs, the most commonly disregulated networks in GBM -- RB, KRAS and\/or PI3K signaling -- are perturbed at the genetic level.\u00a0 These genetic aberrations induce development of high grade astrocytoma in the mouse with properties similar to that of human disease.\u00a0 MRI was used to perform a qualitative and quantitative phenotypic characterization of the different genotypes and molecular subtypes.\u00a0 Additionally, mouse MRI images were compared human GBM imaging parameters using the VASARI lexicon.\u00a0 The MRI data contained herein includes anatomic T2 weighted images and dynamic contrast enhanced MRI.<\/p><p>For scientific or other inquiries about this dataset, please <a rel=\"nofollow\" href=\"http:\/\/www.cancerimagingarchive.net\/support\/\" class=\"external-link\" style=\"text-decoration: underline;text-align: left;\">contact TCIA's Helpdesk<\/a><span style=\"color: rgb(33,37,41);\">.<\/span><\/p><h3 id=\"MouseAstrocytoma-Acknowledgements\">Acknowledgements<\/h3><p><strong style=\"font-size: 16.0px;line-height: 1.5;\"> <span style=\"color: rgb(255,0,0);\"> <span style=\"color: rgb(0,0,0);\">\u00a0<\/span> <\/span> <\/strong>We would like to acknowledge the individuals and institutions that have provided data for this collection:<\/p><ul><li><strong style=\"font-size: 16.0px;line-height: 1.5;\"> <span style=\"color: rgb(255,0,0);\"> <span style=\"color: rgb(0,0,0);\">\u00a0<\/span> <\/span> <\/strong> <span style=\"color: rgb(0,0,0);\"> <strong>National Cancer Institute (Frederick, Maryland) -\u00a0<\/strong>Special thanks to<strong>\u00a0Sunny Jansen, PhD<\/strong>\u00a0 from the Department of\u00a0<\/span> <span style=\"color: rgb(0,0,0);\"> <strong>Mouse Cancer Genetics Program.<\/strong> <\/span><\/li><\/ul><p><br\/><\/p><div class=\"tab-style-builtin\"><div class=\"localtabs-macro\"><div class=\"aui-tabs horizontal-tabs\" role=\"application\" data-aui-responsive=\"true\"><ul class=\"tabs-menu\"><li class=\"menu-item bv-localtab  active-tab \"><a href=\"#24283583ca53014c13374501b6553b43c85b3efd\"><strong>Data Access<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#24283583053a8d68fe2d45db8d3c07ab615f3a52\"><strong>Detailed Description<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#2428358300d8e6a4783547d5af3897aeb1424e2b\"><strong>Citations &amp; Data Usage Policy<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#24283583efbe254128994962986bb6dcff0297df\"><strong>Versions<\/strong><\/a> <\/li><\/ul><div class=\"tabs-pane  active-pane \" id=\"24283583ca53014c13374501b6553b43c85b3efd\" active=\"true\" name=\"Data Access\" ><h3 id=\"MouseAstrocytoma-DataAccess\">Data Access<\/h3><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 59.8809%;\"><colgroup><col style=\"width: 28.5154%;\"\/><col style=\"width: 37.8903%;\"\/><col style=\"width: 33.5878%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\">Images (DICOM, 2.0 GB)<\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><span class=\"confluence-link\">\u00a0<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/24283583\/Mouse-Astrocytoma-doiJNLP.tcia?version=1&amp;modificationDate=1534787031537&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\"> <\/span>\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\" class=\"external-link\" rel=\"nofollow\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><span class=\"confluence-link\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 3.0<\/a><br\/><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>Click the Versions tab for more info about data releases.<\/p><p>\n<h3 id=\"MouseAstrocytoma-AdditionalResourcesforthisDataset\">Additional Resources for this Dataset<\/h3>\n<p>The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.<\/p><\/p><ul><li class=\"auto-cursor-target\"><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=mouse_astrocytoma\" class=\"external-link\" rel=\"nofollow\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li><\/ul><\/div><div class=\"tabs-pane \" id=\"24283583053a8d68fe2d45db8d3c07ab615f3a52\" name=\"Detailed Description\" ><h3 id=\"MouseAstrocytoma-DetailedDescription\">Detailed Description<\/h3><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 19.8589%;\"><colgroup><col style=\"width: 50.2478%;\"\/><col style=\"width: 49.5453%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p>Collection Statistics<\/p><\/div><\/th><th class=\"confluenceTh\"><div class=\"tablesorter-header-inner\"><p><br\/><\/p><\/div><\/th><\/tr><tr><td class=\"confluenceTd\"><p>Modalities<\/p><\/td><td style=\"text-align: center;\" class=\"confluenceTd\"><p>MR<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Participants<\/p><\/td><td style=\"text-align: center;\" class=\"confluenceTd\"><p>48<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Studies<\/p><\/td><td style=\"text-align: center;\" class=\"confluenceTd\"><p>48<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Series<\/p><\/td><td style=\"text-align: center;\" class=\"confluenceTd\"><p>286<\/p><\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Images<\/p><\/td><td style=\"text-align: center;\" class=\"confluenceTd\"><p>37,110<\/p><\/td><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\">Images Size (GB)<\/td><td style=\"text-align: center;\" colspan=\"1\" class=\"confluenceTd\">2.0 GB<\/td><\/tr><\/tbody><\/table><\/div><p><br\/><\/p><p>A presentation about this data set can be found at:\u00a0<strong> <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/24283583\/Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt?version=1&amp;modificationDate=1488927018769&amp;api=v2\" data-linked-resource-id=\"24642133\" data-linked-resource-version=\"1\" data-linked-resource-type=\"attachment\" data-linked-resource-default-alias=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" data-nice-type=\"PowerPoint Presentation\" data-linked-resource-content-type=\"application\/vnd.ms-powerpoint\" data-linked-resource-container-id=\"24283583\" data-linked-resource-container-version=\"24\">Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt<\/a> <\/strong>.<\/p><\/div><div class=\"tabs-pane \" id=\"2428358300d8e6a4783547d5af3897aeb1424e2b\" name=\"Citations BITVOODOO_ANDamp; Data Usage Policy\" ><h3 id=\"MouseAstrocytoma-Citations&amp;DataUsagePolicy\">Citations &amp; Data Usage Policy\u00a0<\/h3><p class=\"auto-cursor-target\">\n<p>\nUsers must abide by the <a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/c4hF\" class=\"external-link\" rel=\"nofollow\">TCIA Data Usage Policy and Restrictions<\/a>. Attribution should include references to the following citations:\n<\/p><\/p><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Data Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p><span style=\"color: rgb(102,102,102);\"> <span style=\"color: rgb(0,0,0);\">Jansen, Sunny, &amp; Van Dyke, Terry. (2015). <strong>TCIA Mouse-Astrocytoma Collection (Mouse-Astrocytoma) [Data set].<\/strong> The Cancer Imaging Archive.<\/span>\u00a0<a href=\"https:\/\/doi.org\/10.7937\/K9TCIA.2017.SGW7CAQW\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.7937\/K9TCIA.2017.SGW7CAQW<\/a> <br\/><\/span><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">TCIA Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p><span style=\"color: rgb(0,0,0);\">Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., &amp; Prior, F. (2013). <\/span><strong>The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository.<\/strong><span style=\"color: rgb(0,0,0);\"> In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045\u20131057). Springer Science and Business Media LLC. <a href=\"https:\/\/doi.org\/10.1007\/s10278-013-9622-7\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.1007\/s10278-013-9622-7<\/a> PMCID: PMC3824915<\/span><\/p><\/div><\/div><h3 id=\"MouseAstrocytoma-OtherPublicationsUsingThisData\">Other Publications Using This Data<\/h3><p><span style=\"color: rgb(33,37,41);\">TCIA maintains<span>\u00a0<\/span><\/span><a style=\"text-decoration: none;text-align: left;\" rel=\"nofollow\" href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\" class=\"external-link\">a list of publications<\/a><span style=\"color: rgb(33,37,41);\"><span>\u00a0<\/span>which leverage our data.<\/span>\u00a0If you have a manuscript you'd like to add, please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\" class=\"external-link\" rel=\"nofollow\">contact TCIA's Helpdesk<\/a>.<\/p><\/div><div class=\"tabs-pane \" id=\"24283583efbe254128994962986bb6dcff0297df\" name=\"Versions\" ><h3 id=\"MouseAstrocytoma-Version1(Current):Updated2017\/03\/21\">Version 1 (Current): Updated 2017\/03\/21<\/h3><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 42.7498%;\"><colgroup> <col style=\"width: 44.5172%;\"\/> <col style=\"width: 55.4797%;\"\/> <\/colgroup><tbody><tr><th colspan=\"1\" class=\"confluenceTh\">Data Type<\/th><th colspan=\"1\" class=\"confluenceTh\">Download all or Query\/Filter<\/th><\/tr><tr><td colspan=\"1\" class=\"confluenceTd\">Images ( 2.0 GB)<\/td><td colspan=\"1\" class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/24283583\/Mouse-Astrocytoma-doiJNLP.tcia?version=1&amp;modificationDate=1534787031537&amp;api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><span class=\"confluence-link\">\u00a0<\/span>\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\" class=\"external-link\" rel=\"nofollow\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\">NBIA Data Retriever<\/a>)<\/p><p><span class=\"confluence-link\"><br\/><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/div><\/div><p><br\/><\/p>","versions":false,"additional_resources":"The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.\n \n<ul><li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=mouse_astrocytoma\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li><\/ul>","cancer_locations":["Head"],"collection_page_accessibility":"Public","publications_related":"","version_change_log":"","version_change_log_archived":"","analysis_results":"","collection_status":"Complete","publications_using":"TCIA maintains\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\">a list of publications<\/a>\u00a0which leverage our data.\u00a0If you have a manuscript you'd like to add, please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.","species":["Mouse"],"collection_title":"Mouse-Astrocytoma","detailed_description":"<br\/>\nA presentation about this data set can be found at:\u00a0<strong> <a data-linked-resource-container-id=\"24283583\" data-linked-resource-container-version=\"24\" data-linked-resource-content-type=\"application\/vnd.ms-powerpoint\" data-linked-resource-default-alias=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" data-linked-resource-id=\"24642133\" data-linked-resource-type=\"attachment\" data-linked-resource-version=\"1\" data-nice-type=\"PowerPoint Presentation\" download=\"\" href=\"\/wp-content\/uploads\/Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" target=\"_blank\">Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt<\/a> <\/strong>.","related_analysis_results":false,"subjects":"48","collection_short_title":"Mouse-Astrocytoma","data_types":["MR"],"date_updated":"2023-09-13","collection_browse_title":"","supporting_data":false,"collection_featured_image":false,"collection_summary":"This collection consists of magnetic resonance images (MRI) of genetically engineered mouse models (GEMMs) of high grade astrocytoma, including glioblastoma multiforme (GBM).\nIn these GEMMs, the most commonly disregulated networks in GBM -- RB, KRAS and\/or PI3K signaling -- are perturbed at the genetic level.\u00a0 These genetic aberrations induce development of high grade astrocytoma in the mouse with properties similar to that of human disease.\u00a0 MRI was used to perform a qualitative and quantitative phenotypic characterization of the different genotypes and molecular subtypes.\u00a0 Additionally, mouse MRI images were compared human GBM imaging parameters using the VASARI lexicon.\u00a0 The MRI data contained herein includes anatomic T2 weighted images and dynamic contrast enhanced MRI.\nFor scientific or other inquiries about this dataset, please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.","collection_acknowledgements":"<strong>  \u00a0  <\/strong>We would like to acknowledge the individuals and institutions that have provided data for this collection:\n<ul><li><strong>  \u00a0  <\/strong> <strong>National Cancer Institute (Frederick, Maryland) -\u00a0<\/strong>Special thanks to<strong>\u00a0Sunny Jansen, PhD<\/strong>\u00a0 from the Department of\u00a0  <strong>Mouse Cancer Genetics Program.<\/strong> <\/li><\/ul>\n<br\/>","collection_funding":"","hide_from_browse_table":[],"_links":{"self":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections\/5629"}],"collection":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections"}],"about":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/types\/tcia_collection"}],"wp:attachment":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media?parent=5629"}],"wp:term":[{"taxonomy":"tcia_citation_tax","embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/v1\/citation-tax?post=5629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}