{"id":5570,"date":"2023-09-04T03:09:08","date_gmt":"2023-09-04T03:09:08","guid":{"rendered":"https:\/\/cm.vastapps.dev\/tcia-collection\/cmb-pca\/"},"modified":"2023-09-13T11:57:42","modified_gmt":"2023-09-13T11:57:42","slug":"cmb-pca","status":"publish","type":"tcia_collection","link":"https:\/\/cm.vastapps.dev\/tcia-collection\/cmb-pca\/","title":{"rendered":"CMB-PCA"},"featured_media":7715,"template":"","citation-tax":[],"cancer_types":["Prostate Cancer"],"citations":[4417,2925,4418],"collection_doi":"10.7937\/25T7-6Y12","collection_download_info":"Click the Versions tab for more info about data releases.","collection_downloads":[4965,4966],"full_export":"<h1 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Summary\">Summary<\/h1><p style=\"text-align: left;\"><span class=\"confluence-embedded-file-wrapper image-right-wrapper confluence-embedded-manual-size\"><img class=\"confluence-embedded-image image-right\" draggable=\"false\" height=\"84\" width=\"600\" src=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/embedded-page\/Public\/Cancer%20Moonshot%20Biobank%20-%20Prostate%20Cancer%20Collection%20(CMB-PCA)\/NIH%20Cancer%20Moonshot%20logo.png?api=v2\"><\/span>The <a href=\"https:\/\/moonshotbiobank.cancer.gov\/\" class=\"external-link\" rel=\"nofollow\">Cancer Moonshot Biobank<\/a> is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated data will be collected longitudinally from at least 1000 patients across at least 10 cancer types, who represent the demographic diversity of the U.S. and receiving <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/standard-of-care\" class=\"external-link\" rel=\"nofollow\">standard of care cancer treatment<\/a> at multiple <a href=\"https:\/\/ncorp.cancer.gov\/\" class=\"external-link\" rel=\"nofollow\">NCI Community Oncology Research Program (NCORP)<\/a> sites.<\/p><p style=\"text-align: left;\">This collection contains de-identified radiology and histopathology imaging procured from subjects in NCI\u2019s Cancer Moonshot Biobank - Prostate Cancer (CMB-PCA) cohort. <span>Associated genomic, phenotypic and clinical data will be hosted by <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/gap\/\" class=\"external-link\" rel=\"nofollow\">The Database of Genotypes and Phenotypes (dbGaP)<\/a> and other NCI databases. \u00a0<span style=\"color: rgb(33,37,41);\">A summary of Cancer Moonshot Biobank imaging efforts can be found on the\u00a0<\/span><u style=\"text-align: left;\"><a style=\"text-decoration: none;\" class=\"external-link\" rel=\"nofollow\" href=\"https:\/\/www.cancerimagingarchive.net\/research\/cmb\/\">Cancer Moonshot Biobank Imaging<\/a><\/u><span style=\"color: rgb(33,37,41);\">\u00a0page.<\/span><\/span><\/p><p><br\/><\/p><div class=\"tab-style-builtin\"><div class=\"localtabs-macro\"><div class=\"aui-tabs horizontal-tabs\" role=\"application\" data-aui-responsive=\"true\"><ul class=\"tabs-menu\"><li class=\"menu-item bv-localtab  active-tab \"><a href=\"#952240820a603347366648bdb679fbf218b3e775\"><strong>Data Access<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#952240820ad052fc343543aa86f56f9c4cbfec99\"><strong>Detailed Description<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#952240825f6fddc278a247189661746bdd0a99a2\"><strong>Citations &amp; Data Usage Policy<\/strong><\/a> <\/li><li class=\"menu-item bv-localtab \"><a href=\"#952240829f78062d6f384545ae8c6c598df91e9f\"><strong>Versions<\/strong><\/a> <\/li><\/ul><div class=\"tabs-pane  active-pane \" id=\"952240820a603347366648bdb679fbf218b3e775\" active=\"true\" name=\"Data Access\" ><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-DataAccess\">Data Access<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup><col\/><col\/><col\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Images (DICOM, 2 GB)<\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/95224082\/CMB-PCA%20manifest%20August%2029%202022.tcia?api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=CMB-PCA\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><br\/><\/p><p><span style=\"color: rgb(33,37,41);text-decoration: none;\">(Download requires\u00a0<\/span><span style=\"color: rgb(33,37,41);text-decoration: none;\">the<span>\u00a0<\/span><\/span><a rel=\"nofollow\" href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" style=\"text-decoration: none;text-align: left;\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\"><span style=\"color: rgb(33,37,41);\">Tissue Slide Images, <span>\u00a0<\/span>Pathology Metadata (SVS, JSON, 0.582 GB)<\/span><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/faspex.cancerimagingarchive.net\/aspera\/faspex\/external_deliveries\/317?passcode=ee007f57d51338561d7d68532503736eebde05af\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/pathdb.cancerimagingarchive.net\/eaglescope\/dist\/?configurl=%2Fsystem%2Ffiles%2Fcollectionmetadata%2F202208%2Fbiobank_metadata_page_first50_4.json&amp;filterState=%5B%7B%22id%22%3A%22TCIA_Collection%22%2C%22title%22%3A%22Collection%22%2C%22field%22%3A%22TCIA_Collection%22%2C%22operation%22%3A%22eq%22%2C%22values%22%3A%22CMB-PCA%22%7D%5D\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><\/p><p class=\"auto-cursor-target\"><span style=\"color: rgb(33,37,41);\">(Download requires<span>\u00a0<\/span><\/span><a style=\"text-decoration: none;text-align: left;\" rel=\"nofollow\" href=\"https:\/\/www.ibm.com\/aspera\/connect\/\" class=\"external-link\">Aspera<\/a><span style=\"color: rgb(33,37,41);\">)<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p class=\"auto-cursor-target\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p>Click the Versions tab for more info about data releases.<\/p><p>\n<h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-AdditionalResourcesforthisDataset\">Additional Resources for this Dataset<\/h3>\n<p>The database of Genotypes and Phenotypes (dbGaP) hosts genomic, phenotypic, and clinical data for NCI's Cancer Moonshot Biobank (CMB) project. Information and access to the data can be found at: \n<\/p><ul><li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/projects\/gap\/cgi-bin\/study.cgi?study_id=phs002192.v1.p1\" class=\"external-link\" rel=\"nofollow\">dbGaP - Cancer Moonshot Biobank<\/a> (Genomic, Phenotypic &amp; Clinical Data)<\/li><\/ul>\n<p \/><\/p><p><span style=\"color: rgb(33,37,41);\">The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.<\/span><\/p><ul style=\"text-align: left;\"><li class=\"auto-cursor-target\"><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=cmb_pca\" class=\"external-link\" rel=\"nofollow\">Imaging Data Commons (IDC)<\/a><span>\u00a0<\/span>(Imaging Data)<\/li><\/ul><\/div><div class=\"tabs-pane \" id=\"952240820ad052fc343543aa86f56f9c4cbfec99\" name=\"Detailed Description\" ><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-DetailedDescription\">Detailed Description<\/h3><div class=\"table-wrap\"><table class=\"wrapped relative-table confluenceTable\" style=\"width: 24.0981%;\"><colgroup><col style=\"width: 35.1491%;\"\/><col style=\"width: 30.6715%;\"\/><col style=\"width: 34.0297%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\"><p>Image Statistics<\/p><\/th><th class=\"confluenceTh\">Radiology Image Statistics<\/th><th class=\"confluenceTh\">Pathology Image Statistics<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Modalities<\/p><\/td><td class=\"confluenceTd\"><p>CT, MR, NM<\/p><\/td><td class=\"confluenceTd\">WSI<\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Patients<\/p><\/td><td class=\"confluenceTd\">3<\/td><td class=\"confluenceTd\">3<\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Studies<\/p><\/td><td class=\"confluenceTd\"><p>6<\/p><\/td><td class=\"confluenceTd\">N\/A<\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Series<\/p><\/td><td class=\"confluenceTd\"><p>31<\/p><\/td><td class=\"confluenceTd\">N\/A<\/td><\/tr><tr><td class=\"confluenceTd\"><p>Number of Images<\/p><\/td><td class=\"confluenceTd\">2941<\/td><td class=\"confluenceTd\">3<\/td><\/tr><tr><td class=\"confluenceTd\">Images Size (GB)<\/td><td class=\"confluenceTd\">2<\/td><td class=\"confluenceTd\">0.582<\/td><\/tr><\/tbody><\/table><\/div><p class=\"auto-cursor-target\"><h2 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Introduction\">Introduction<\/h2><p>Biobank radiology imaging data on TCIA contains the \u201cdays from enrollment (registration)\u201d for each scan, embedded in the DICOM files (DICOM tag (0012,0053)). \u00a0 This allows for temporal alignment between the imaging on TCIA and clinical events data found on the Biobank Catalog.<br\/>Note: \u00a0In order that the images display properly in DICOM readers, the radiology imaging data also contains de-identified dates that preserve the temporal sequence relationship between scans in a given study.<\/p><h2 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Daysfromenrollment(registration)\">Days from enrollment (registration)\u00a0<\/h2><p style=\"text-align: left;\">In addition to modifying the actual date fields in the DICOM header, the &quot;days from registration&quot; values are calculated and stored in the DICOM tag<strong><span style=\"color: inherit;\">\u00a0<\/span>(0012,0052)<span style=\"color: inherit;\">\u00a0<\/span><span style=\"color: rgb(34,34,34);\">Longitudinal Temporal Offset from Event<\/span><\/strong><span style=\"color: inherit;\">\u00a0<\/span>with the associated tag<span style=\"color: inherit;\">\u00a0<\/span><strong>(0012,0053) Longitudinal Temporal Event Type<\/strong><span style=\"color: inherit;\">\u00a0<\/span>set to \u201cREGISTRATION\u201d.\u00a0 \u00a0Here is an example DICOM header from a scan where the patient's imaging was performed 2 days before the registration, resulting in a negative offset value.<\/p><div class=\"table-wrap\"><table style=\"text-align: left;\" class=\"confluenceTable\"><tbody><tr><td class=\"confluenceTd\">(0012,0052)<\/td><td class=\"confluenceTd\">Longitudinal Temporal Offset from Event<\/td><td class=\"confluenceTd\">-2.0<\/td><\/tr><tr><td class=\"confluenceTd\">(0012,0053)<\/td><td class=\"confluenceTd\">Longitudinal Temporal Event Type<\/td><td class=\"confluenceTd\">REGISTRATION<\/td><\/tr><\/tbody><\/table><\/div><p class=\"auto-cursor-target\">If you would like to filter your search results using this information, you can leverage the &quot;Clinical Trial Time Points&quot; filter\u00a0 via our data portal at <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/\" class=\"external-link\" rel=\"nofollow\">https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/<\/a>.\u00a0<\/p><p class=\"auto-cursor-target\"><span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\"><img class=\"confluence-embedded-image confluence-content-image-border\" draggable=\"false\" height=\"400\" width=\"496\" src=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/embedded-page\/Public\/Cancer%20Moonshot%20Biobank%20Date%20Handling\/image2022-8-23_11-46-31.png?api=v2\"><\/span><\/p><h2 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-De-identificationofDICOMdates\">De-identification of DICOM dates<\/h2><p>De-identification of dates for this dataset uses the DICOM Part 3.15 Annex E standard \u201cRetain Longitudinal With Modified Dates Option\u201d which allows dates to be retained as long as they are modified from the original date.\u00a0 TCIA implements this using a technique which de-identifies the dates while preserving the longitudinal relationship between them. \u00a0<span style=\"color: red;\"><span style=\"color: black;\">Original dates will be first normalized to January 1, 1960 and then offset relative to the date of registration for each patient.\u00a0 This normalized date system was chosen in order to make it obvious that the dates are not real, and to make it easy to quickly determine how much time has passed between the date of registration and the patients' related imaging studies.\u00a0<\/span><\/span><\/p><p>For example, if the real date of a patient's registration was 03\/27\/2018 and the original imaging Study Date was 03\/29\/2018 then the anonymized TCIA Study Date would become 01\/03\/1960 (two days after the base date of 1\/1\/1960).<\/p><\/p><\/div><div class=\"tabs-pane \" id=\"952240825f6fddc278a247189661746bdd0a99a2\" name=\"Citations BITVOODOO_ANDamp; Data Usage Policy\" ><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Citations&amp;DataUsagePolicy\">Citations &amp; Data Usage Policy<\/h3><p>\n<p>\nUsers must abide by the <a href=\"https:\/\/wiki.cancerimagingarchive.net\/x\/c4hF\" class=\"external-link\" rel=\"nofollow\">TCIA Data Usage Policy and Restrictions<\/a>. Attribution should include references to the following citations:\n<\/p><\/p><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Data Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p class=\"p1\"><span style=\"color: rgb(0,0,0);\">Cancer Moonshot Biobank. (2022). Cancer Moonshot Biobank - Prostate Cancer Collection (CMB-PCA) (Version 2) [Data set]. The Cancer Imaging Archive<\/span>. <a href=\"https:\/\/doi.org\/10.7937\/25T7-6Y12\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.7937\/25T7-6Y12<\/a><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">Acknowledgement<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p><span style=\"color: rgb(34,34,34);\">The Cancer Moonshot Biobank program requests that publications using data from this program include the following statement: \u201c<\/span><strong style=\"text-align: left;\">Data used in this publication were generated by the National Cancer Institute Cancer Moonshot Biobank<\/strong><span style=\"color: rgb(34,34,34);\">.\u201d<\/span><\/p><\/div><\/div><div class=\"confluence-information-macro confluence-information-macro-information\"><p class=\"title\">TCIA Citation<\/p><span class=\"aui-icon aui-icon-small aui-iconfont-info confluence-information-macro-icon\"><\/span><div class=\"confluence-information-macro-body\"><p class=\"p1\">Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., &amp; Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045\u20131057). Springer Science and Business Media LLC. <a href=\"https:\/\/doi.org\/10.1007\/s10278-013-9622-7\" class=\"external-link\" rel=\"nofollow\">https:\/\/doi.org\/10.1007\/s10278-013-9622-7<\/a><\/p><\/div><\/div><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-OtherPublicationsUsingThisData\">Other Publications Using This Data<\/h3><p><span>TCIA maintains\u00a0<\/span><a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\" class=\"external-link\" rel=\"nofollow\">a list of publications<\/a><span> which leverage TCIA data. <\/span> If you have a manuscript you'd like to add please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\" class=\"external-link\" rel=\"nofollow\"> contact the TCIA Helpdesk<\/a>.<\/p><\/div><div class=\"tabs-pane \" id=\"952240829f78062d6f384545ae8c6c598df91e9f\" name=\"Versions\" ><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Version1(Current):Updated2022\/08\/29\">Version 1 (Current): Updated 2022\/08\/29<\/h3><div class=\"table-wrap\"><table class=\"wrapped confluenceTable\"><colgroup><col\/><col\/><col\/><\/colgroup><tbody><tr><th class=\"confluenceTh\">Data Type<\/th><th class=\"confluenceTh\">Download all or Query\/Filter<\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\"><p>Images (DICOM, 2 GB)<\/p><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/wiki.cancerimagingarchive.net\/download\/attachments\/95224082\/CMB-PCA%20manifest%20August%2029%202022.tcia?api=v2\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=CMB-PCA\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><br\/><\/p><p><span style=\"color: rgb(33,37,41);text-decoration: none;\">(Download requires\u00a0<\/span><span style=\"color: rgb(33,37,41);text-decoration: none;\">the<span>\u00a0<\/span><\/span><a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\" style=\"text-decoration: none;text-align: left;\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\"><span style=\"color: rgb(33,37,41);\">Tissue Slide Images (SVS, 0.582 GB)<\/span><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/faspex.cancerimagingarchive.net\/aspera\/faspex\/external_deliveries\/317?passcode=ee007f57d51338561d7d68532503736eebde05af\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/pathdb.cancerimagingarchive.net\/eaglescope\/dist\/?configurl=%2Fsystem%2Ffiles%2Fcollectionmetadata%2F202208%2Fbiobank_metadata_page_first50_4.json&amp;filterState=%5B%7B%22id%22%3A%22TCIA_Collection%22%2C%22title%22%3A%22Collection%22%2C%22field%22%3A%22TCIA_Collection%22%2C%22operation%22%3A%22eq%22%2C%22values%22%3A%22CMB-PCA%22%7D%5D\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><\/p><p class=\"auto-cursor-target\"><span style=\"color: rgb(33,37,41);\">(Download requires<span>\u00a0<\/span><\/span><a class=\"external-link\" rel=\"nofollow\" style=\"text-decoration: none;text-align: left;\" href=\"https:\/\/www.ibm.com\/aspera\/connect\/\">Aspera<\/a><span style=\"color: rgb(33,37,41);\">)<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p class=\"auto-cursor-target\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><p class=\"p1\">Note: Removed Scout and similar series (Scout, Topogram, Localizer, and 1 Sec Capture) that did not have corresponding MR\/CT image series.<\/p><h3 id=\"CancerMoonshotBiobankProstateCancerCollection(CMBPCA)-Version1:Updated2022\/08\/12\">Version 1: Updated 2022\/08\/12<\/h3><div class=\"table-wrap\"><table class=\"wrapped fixed-width confluenceTable\" style=\"width: 46.4015%;\"><colgroup><col style=\"width: 33.3148%;\"\/><col style=\"width: 42.369%;\"\/><col style=\"width: 24.2715%;\"\/><\/colgroup><tbody><tr><th class=\"confluenceTh\"><span>Data Type<\/span><\/th><th class=\"confluenceTh\"><span>Download all or Query\/Filter<\/span><\/th><th class=\"confluenceTh\">License<\/th><\/tr><tr><td class=\"confluenceTd\"><span>Images (DICOM, 2 GB)<\/span><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=CMB-PCA\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><br\/><\/p><p>(Requires\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\" rel=\"nofollow\">NBIA Data Retriever<\/a><span>.<\/span>)<\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p>\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><tr><td class=\"confluenceTd\"><span style=\"color: rgb(33,37,41);\">Tissue Slide Images (SVS, 0.582 GB)<\/span><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p><br\/>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/faspex.cancerimagingarchive.net\/aspera\/faspex\/external_deliveries\/317?passcode=ee007f57d51338561d7d68532503736eebde05af\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-download-color\"><i class=\"fa fa-cloud-download\" \/> Download<\/button><\/a>\u00a0\n<\/span>\n\n<span class=\"confluence-embedded-file-wrapper confluence-embedded-manual-size\">\n   <a href=\"https:\/\/pathdb.cancerimagingarchive.net\/eaglescope\/dist\/?configurl=%2Fsystem%2Ffiles%2Fcollectionmetadata%2F202208%2Fbiobank_metadata_page_first50_4.json&amp;filterState=%5B%7B%22id%22%3A%22TCIA_Collection%22%2C%22title%22%3A%22Collection%22%2C%22field%22%3A%22TCIA_Collection%22%2C%22operation%22%3A%22eq%22%2C%22values%22%3A%22CMB-PCA%22%7D%5D\" class=\"external-link\" rel=\"nofollow\"><button class=\"tcia-btn tcia-search-color\"><i class=\"fa fa-search\" \/> Search<\/button><\/a>\u00a0\n<\/span><\/p><p class=\"auto-cursor-target\"><span style=\"color: rgb(33,37,41);\">(Download requires<span>\u00a0<\/span><\/span><a rel=\"nofollow\" style=\"text-decoration: none;text-align: left;\" class=\"external-link\" href=\"https:\/\/www.ibm.com\/aspera\/connect\/\">Aspera<\/a><span style=\"color: rgb(33,37,41);\">)<\/span><\/p><\/div><\/td><td class=\"confluenceTd\"><div class=\"content-wrapper\"><p class=\"auto-cursor-target\">\n<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" class=\"external-link\" rel=\"nofollow\">CC BY 4.0<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/div><\/div><p><br\/><\/p><p><br\/><\/p><p><br\/><\/p><p><br\/><\/p>","versions":false,"additional_resources":"The database of Genotypes and Phenotypes (dbGaP) hosts genomic, phenotypic, and clinical data for NCI's Cancer Moonshot Biobank (CMB) project. Information and access to the data can be found at: \n\n<ul><li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/projects\/gap\/cgi-bin\/study.cgi?study_id=phs002192.v1.p1\">dbGaP - Cancer Moonshot Biobank<\/a> (Genomic, Phenotypic &amp; Clinical Data)<\/li><\/ul>\n \n \nThe NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.\n<ul><li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=cmb_pca\">Imaging Data Commons (IDC)<\/a>\u00a0(Imaging Data)<\/li><\/ul>","cancer_locations":["Prostate"],"collection_page_accessibility":"Public","publications_related":"","version_change_log":"","version_change_log_archived":"","analysis_results":"","collection_status":"Ongoing","publications_using":"TCIA maintains\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\">a list of publications<\/a> which leverage TCIA data.  If you have a manuscript you'd like to add please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\"> contact the TCIA Helpdesk<\/a>.","species":["Human"],"collection_title":"Cancer Moonshot Biobank - Prostate Cancer Collection","detailed_description":"<h3>Introduction<\/h3><p>Biobank radiology imaging data on TCIA contains the \u201cdays from enrollment (registration)\u201d for each scan, embedded in the DICOM files (DICOM tag (0012,0053)). \u00a0 This allows for temporal alignment between the imaging on TCIA and clinical events data found on the Biobank Catalog.<br\/>Note: \u00a0In order that the images display properly in DICOM readers, the radiology imaging data also contains de-identified dates that preserve the temporal sequence relationship between scans in a given study.<\/p><h3>Days from enrollment (registration)\u00a0<\/h3><p>In addition to modifying the actual date fields in the DICOM header, the \"days from registration\" values are calculated and stored in the DICOM tag<strong>\u00a0(0012,0052)\u00a0Longitudinal Temporal Offset from Event<\/strong>\u00a0with the associated tag\u00a0<strong>(0012,0053) Longitudinal Temporal Event Type<\/strong>\u00a0set to \u201cREGISTRATION\u201d.\u00a0 \u00a0Here is an example DICOM header from a scan where the patient's imaging was performed 2 days before the registration, resulting in a negative offset value.<\/p><div><table><tbody><tr><td>(0012,0052)<\/td><td>Longitudinal Temporal Offset from Event<\/td><td>-2.0<\/td><\/tr><tr><td>(0012,0053)<\/td><td>Longitudinal Temporal Event Type<\/td><td>REGISTRATION<\/td><\/tr><\/tbody><\/table><\/div><p>If you would like to filter your search results using this information, you can leverage the \"Clinical Trial Time Points\" filter\u00a0 via our data portal at <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/\">https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/<\/a>.\u00a0<\/p><p><div class=\"cm-content-image\"><a href=\"\/wp-content\/uploads\/image2022-8-23_11-46-31.png\" rel=\"prettyPhoto noopener\" target=\"_blank\"><img src=\"\/wp-content\/uploads\/image2022-8-23_11-46-31.png\"\/><\/a><\/div><\/p><h3>De-identification of DICOM dates<\/h3><p>De-identification of dates for this dataset uses the DICOM Part 3.15 Annex E standard \u201cRetain Longitudinal With Modified Dates Option\u201d which allows dates to be retained as long as they are modified from the original date.\u00a0 TCIA implements this using a technique which de-identifies the dates while preserving the longitudinal relationship between them. \u00a0Original dates will be first normalized to January 1, 1960 and then offset relative to the date of registration for each patient.\u00a0 This normalized date system was chosen in order to make it obvious that the dates are not real, and to make it easy to quickly determine how much time has passed between the date of registration and the patients' related imaging studies.\u00a0<\/p><p>For example, if the real date of a patient's registration was 03\/27\/2018 and the original imaging Study Date was 03\/29\/2018 then the anonymized TCIA Study Date would become 01\/03\/1960 (two days after the base date of 1\/1\/1960).<\/p>","related_analysis_results":false,"subjects":"3","collection_short_title":"CMB-PCA","data_types":["CT","MR","NM"],"date_updated":"2023-09-13","collection_browse_title":"","supporting_data":["Clinical","Pathology"],"collection_featured_image":{"ID":"7715","post_author":"6","post_date":"2023-09-13 03:40:01","post_date_gmt":"2023-09-13 03:40:01","post_content":"","post_title":"NIH-Cancer-Moonshot-logo","post_excerpt":"","post_status":"inherit","comment_status":"open","ping_status":"closed","post_password":"","post_name":"nih-cancer-moonshot-logo","to_ping":"","pinged":"","post_modified":"2023-09-13 11:57:26","post_modified_gmt":"2023-09-13 11:57:26","post_content_filtered":"","post_parent":"5563","guid":"https:\/\/cm.vastapps.dev\/wp-content\/uploads\/NIH-Cancer-Moonshot-logo.png","menu_order":"0","post_type":"attachment","post_mime_type":"image\/png","comment_count":"0","pod_item_id":"7715"},"collection_summary":"The <a href=\"https:\/\/moonshotbiobank.cancer.gov\/\">Cancer Moonshot Biobank<\/a> is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated data will be collected longitudinally from at least 1000 patients across at least 10 cancer types, who represent the demographic diversity of the U.S. and receiving <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/standard-of-care\">standard of care cancer treatment<\/a> at multiple <a href=\"https:\/\/ncorp.cancer.gov\/\">NCI Community Oncology Research Program (NCORP)<\/a> sites.<p>This collection contains de-identified radiology and histopathology imaging procured from subjects in NCI\u2019s Cancer Moonshot Biobank - Prostate Cancer (CMB-PCA) cohort. Associated genomic, phenotypic and clinical data will be hosted by <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/gap\/\">The Database of Genotypes and Phenotypes (dbGaP)<\/a> and other NCI databases. \u00a0A summary of Cancer Moonshot Biobank imaging efforts can be found on the\u00a0<u><a href=\"https:\/\/www.cancerimagingarchive.net\/research\/cmb\/\">Cancer Moonshot Biobank Imaging<\/a><\/u>\u00a0page.<\/p>\n<br\/>","collection_acknowledgements":"","collection_funding":"","hide_from_browse_table":[],"_links":{"self":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections\/5570"}],"collection":[{"href":"https:\/\/cm.vastapps.dev\/api\/v1\/collections"}],"about":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/types\/tcia_collection"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media\/7715"}],"wp:attachment":[{"href":"https:\/\/cm.vastapps.dev\/api\/wp\/v2\/media?parent=5570"}],"wp:term":[{"taxonomy":"tcia_citation_tax","embeddable":true,"href":"https:\/\/cm.vastapps.dev\/api\/v1\/citation-tax?post=5570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}