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RIDER-LungCT-Seg | RIDER Lung CT Segmentation Labels from: Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach

DOI: 10.7937/tcia.2020.jit9grk8 | Page Accessibility: Public | Analysis Result

Analysis Result Snapshot
Cancer Types Location Subjects Related Collections Supporting Data Updated
Lung Chest 31 Tumor segmentations 02/13/2020

Summary

This dataset contains images from 31 out of the 32 non-small cell lung cancer (NSCLC) patients in the RIDER Lung CT collection on TCIA. For these subjects a radiation oncologist was blinded to the all delineations of the 3D volume of the gross tumor volume. They were then asked to manually delineate the gross tumour volume in both the test image and the re-test image. The process was repeated using an in-house autosegmentation method. There is no clinical outcome data associated with this dataset.

This dataset refers to the RIDER dataset of the study published in Nature Communications (http://doi.org/10.1038/ncomms5006). In short, this publication used the dataset to select for repeatable radiomics features in a test-retest context. Radiomics refers to the comprehensive quantification of tumour phenotypes by applying a large number of quantitative image features. In the published analysis, 440 features quantifying tumour image intensity, shape and texture, were extracted. We found that a large number of radiomic features have prognostic power in independent data sets, many of which were not identified as significant before. Radiogenomics analysis revealed that a prognostic radiomic signature, capturing intra-tumour heterogeneity, was associated with underlying gene-expression patterns. These data suggest that radiomics identifies a general prognostic phenotype existing in both lung and head-and-neck cancer. This may have a clinical impact as imaging is routinely used in clinical practice, providing an unprecedented opportunity to improve decision-support in cancer treatment at low cost.

Other data sets in the Cancer Imaging Archive that were used in the same study published in Nature Communications: NSCLC-Radiomics, NSCLC-Radiomics-Genomics, NSCLC-Radiomics-Interobserver1, HEAD-NECK-RADIOMICS-HN1.  

Data Access

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Title Data Type Format Access Points Studies Series Images License
Gross Tumor Volume Segmentation - RTSTRUCT, SEG DICOM, RTSTRUCT, and SEG 31 118 118 CC BY 3.0

Collections Used in this Third Party Analysis

Title Data Type Format Access Points Studies Series Images License
Corresponding Original CT Images from RIDER Lung CT - DICOM CC BY 3.0

Detailed Description

  • (RIDER-2283289298) only has segmentations associated with the retest.

  • (RIDER-5195703382) only has segmentations associated with the test.

  • (RIDER-8509201188) only has segmentations associated with the test.

  • (RIDER-9762593735) not included in the data set due to missing delineations.

Citations & Data Usage Policy

Data Citation

Wee, L., Aerts, H., Kalendralis, P., & Dekker, A. (2020). RIDER Lung CT Segmentation Labels from: Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/tcia.2020.jit9grk8

Publication Citation

Aerts, H. J. W. L., Velazquez, E. R., Leijenaar, R. T. H., Parmar, C., Grossmann, P., Carvalho, S., Bussink, J., Monshouwer, R., Haibe-Kains, B., Rietveld, D., Hoebers, F., Rietbergen, M. M., Leemans, C. R., Dekker, A., Quackenbush, J., Gillies, R. J., & Lambin, P. (2014). Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nature Communications, 5(1). https://doi.org/10.1038/ncomms5006

TCIA Citation

Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045–1057). Springer Science and Business Media LLC. https://doi.org/10.1007/s10278-013-9622-7

Other Publications Using This Data

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Collections Used In This Analysis Result

Collections Used In This Analysis Result